Showing results (1-10 of 7) with videos related to
Sort By:
Pageof 1
The Journal of Organic Chemistry|January 5, 2002
The versatility of alpha-chloropropargyl phenyl sulfide affords high stereo- and regioselectivities in indium-promoted coupling reactions under mild conditionsThomas M Mitzel, Carolyn Palomo, Keith JendzaACS Medicinal Chemistry Letters|January 19, 2019
Discovery of TD-0212, an Orally Active Dual Pharmacology AT<sub>1</sub> Antagonist and Neprilysin Inhibitor (ARNI)R Murray McKinnell, Paul Fatheree, Seok-Ki Choi, et al.ACS Medicinal Chemistry Letters|December 20, 2023
Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 AgonistsChristopher G Thomson, Kelly Boss, Amy Calhoun, et al.Nature Chemical Biology|June 19, 2019
A small-molecule inhibitor of C5 complement proteinKeith Jendza, Mitsunori Kato, Michael Salcius, et al.Journal of Medicinal Chemistry|April 18, 2019
Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement PathwayRajeshri G Karki, James Powers, Nello Mainolfi, et al.Journal of Medicinal Chemistry|February 6, 2018
The Discovery of N-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular DegenerationChristopher M Adams, Karen Anderson, Gerald Artman, et al.Journal of Medicinal Chemistry|February 20, 2020
Discovery of 4-((2<i>S</i>,4<i>S</i>)-4-Ethoxy-1-((5-methoxy-7-methyl-1<i>H</i>-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated DiseasesNello Mainolfi, Takeru Ehara, Rajeshri G Karki, et al.Pageof 1