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Acta Crystallographica. Section D, Structural Biology|September 3, 2020
Targeting the innate immune receptor TLR8 using small-molecule agents. CorrigendumKentaro Sakaniwa, Toshiyuki Shimizu
Acta Crystallographica. Section D, Structural Biology|July 7, 2020
Targeting the innate immune receptor TLR8 using small-molecule agentsKentaro Sakaniwa, Toshiyuki Shimizu
Structure (London, England : 1993)|December 25, 2024
The structures of the peptide transporters SLC15A3 and SLC15A4 reveal the recognition mechanisms for substrate and TASLZhikuan Zhang, Shota Kasai, Kentaro Sakaniwa, et al.
Journal of Medicinal Chemistry|November 6, 2019
Discovery of Novel Small Molecule Dual Inhibitors Targeting Toll-Like Receptors <b>7</b> and <b>8</b>Rosaura Padilla-Salinas, Rachel Anderson, Kentaro Sakaniwa, et al.
European Journal of Pharmacology|August 6, 2023
A novel Toll-like receptor 7/8-specific antagonist E6742 ameliorates clinically relevant disease parameters in murine models of lupusSally T Ishizaka, Lynn Hawkins, Qian Chen, et al.
Nature Communications|January 11, 2023
TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transductionKentaro Sakaniwa, Akiko Fujimura, Takuma Shibata, et al.
Cell Chemical Biology|August 14, 2018
Small-Molecule TLR8 Antagonists via Structure-Based Rational DesignZhenyi Hu, Hiromi Tanji, Shuangshuang Jiang, et al.
Journal of Medicinal Chemistry|April 3, 2020
Rationally Designed Small-Molecule Inhibitors Targeting an Unconventional Pocket on the TLR8 Protein-Protein InterfaceShuangshuang Jiang, Hiromi Tanji, Kejun Yin, et al.
Nature Chemical Biology|November 21, 2017
Small-molecule inhibition of TLR8 through stabilization of its resting stateShuting Zhang, Zhenyi Hu, Hiromi Tanji, et al.
Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan|February 3, 2016
[Structural Analyses of Toll-like Receptor Sensing Single-stranded Nucleic Acids and Its Application]Toshiyuki Shimizu
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