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Chemical Research in Toxicology
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September 20, 2012
Insights into the novel hydrolytic mechanism of a diethyl 2-phenyl-2-(2-arylacetoxy)methyl malonate ester-based microsomal triglyceride transfer protein (MTP) inhibitor
Tim Ryder, Gregory S Walker, Theunis C Goosen, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
September 9, 2018
6-Chloro-5-[4-(1-Hydroxycyclobutyl)Phenyl]-1<i>H</i>-Indole-3-Carboxylic Acid is a Highly Selective Substrate for Glucuronidation by UGT1A1, Relative to <i>β</i>-Estradiol
Kimberly Lapham, Jian Lin, Jonathan Novak, et al.
Chemical Research in Toxicology
|
September 28, 2016
Inhibition of Hepatobiliary Transport Activity by the Antibacterial Agent Fusidic Acid: Insights into Factors Contributing to Conjugated Hyperbilirubinemia/Cholestasis
Kimberly Lapham, Jonathan Novak, Lisa D Marroquin, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 4, 2007
Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production
Lain-Yen Hu, Huangshu John Lei, Daniel Du, et al.
Journal of Medicinal Chemistry
|
December 21, 2016
Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality
Christopher R Butler, Kevin Ogilvie, Luis Martinez-Alsina, et al.
ACS Medicinal Chemistry Letters
|
February 21, 2015
Evaluation and synthesis of polar aryl- and heteroaryl spiroazetidine-piperidine acetamides as ghrelin inverse agonists
Suvi T M Orr, Ramsay Beveridge, Samit K Bhattacharya, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate
Samit K Bhattacharya, Kim Andrews, Ramsay Beveridge, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 11, 2007
(1R,2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production
Lain-Yen Hu, Daniel Du, Jennifer Hoffman, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 20, 2013
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor
Kim F McClure, Margaret Jackson, Kimberly O Cameron, et al.
Journal of Medicinal Chemistry
|
December 23, 2022
Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4
Allyn T Londregan, Karlygash Aitmakhanova, James Bennett, et al.
Page
of 3
Search research articles
Search
Showing results (11-20 of 21) with videos related to
Sort By:
Page
of 3
Chemical Research in Toxicology
|
September 20, 2012
Insights into the novel hydrolytic mechanism of a diethyl 2-phenyl-2-(2-arylacetoxy)methyl malonate ester-based microsomal triglyceride transfer protein (MTP) inhibitor
Tim Ryder, Gregory S Walker, Theunis C Goosen, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
September 9, 2018
6-Chloro-5-[4-(1-Hydroxycyclobutyl)Phenyl]-1<i>H</i>-Indole-3-Carboxylic Acid is a Highly Selective Substrate for Glucuronidation by UGT1A1, Relative to <i>β</i>-Estradiol
Kimberly Lapham, Jian Lin, Jonathan Novak, et al.
Chemical Research in Toxicology
|
September 28, 2016
Inhibition of Hepatobiliary Transport Activity by the Antibacterial Agent Fusidic Acid: Insights into Factors Contributing to Conjugated Hyperbilirubinemia/Cholestasis
Kimberly Lapham, Jonathan Novak, Lisa D Marroquin, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 4, 2007
Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production
Lain-Yen Hu, Huangshu John Lei, Daniel Du, et al.
Journal of Medicinal Chemistry
|
December 21, 2016
Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality
Christopher R Butler, Kevin Ogilvie, Luis Martinez-Alsina, et al.
ACS Medicinal Chemistry Letters
|
February 21, 2015
Evaluation and synthesis of polar aryl- and heteroaryl spiroazetidine-piperidine acetamides as ghrelin inverse agonists
Suvi T M Orr, Ramsay Beveridge, Samit K Bhattacharya, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate
Samit K Bhattacharya, Kim Andrews, Ramsay Beveridge, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 11, 2007
(1R,2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production
Lain-Yen Hu, Daniel Du, Jennifer Hoffman, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 20, 2013
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor
Kim F McClure, Margaret Jackson, Kimberly O Cameron, et al.
Journal of Medicinal Chemistry
|
December 23, 2022
Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4
Allyn T Londregan, Karlygash Aitmakhanova, James Bennett, et al.
Page
of 3