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Frontiers in Genetics|January 11, 2021
Review: <i>In vitro</i> Cell Platform for Understanding Developmental ToxicityJunkai Xie, Kyle Wettschurack, Chongli Yuan
Trends in Molecular Medicine|October 29, 2025
Precision medicine for sodium channelopathy-related autism and epilepsyMorgan Robinson, Kyle Wettschurack, Manasi S Halurkar, et al.
Neurobiology of Disease|March 18, 2022
Deficiency of autism-related Scn2a gene in mice disrupts sleep patterns and circadian rhythmsZhixiong Ma, Muriel Eaton, Yushuang Liu, et al.
Biorxiv : the Preprint Server for Biology|June 12, 2025
Human microglia in brain assembloids display region- specific diversity and respond to hyperexcitable neurons carrying <i>SCN2A</i> mutation: Microglial diversity and response in assembloidsJiaxiang Wu, Xiaoling Chen, Jingliang Zhang, et al.
Science Advances|February 18, 2026
Human microglia in brain assembloids display region-specific diversity and respond to hyperexcitable neurons carrying <i>SCN2A</i> mutationJiaxiang Wu, Xiaoling Chen, Jingliang Zhang, et al.
Research Square|October 16, 2023
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoidsYang Yang, Jiaxiang Wu, Jingliang Zhang, et al.
Biorxiv : the Preprint Server for Biology|November 14, 2023
Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated SCN2A-L1342P mutationZhefu Que, Maria I Olivero-Acosta, Ian Chen, et al.
Biorxiv : the Preprint Server for Biology|September 2, 2025
Epilepsy-Associated SCN2A-L1342P Mutation Drives Network Hyperexcitability and Widespread Transcriptomic Changes in Human Cortical OrganoidsMaria I Olivero-Acosta, Morgan Robinson, Zhefu Que, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|October 30, 2021
Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic VariantZhefu Que, Maria I Olivero-Acosta, Jingliang Zhang, et al.
Molecular Psychiatry|March 19, 2024
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoidsJiaxiang Wu, Jingliang Zhang, Xiaoling Chen, et al.
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