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Trends in Cell Biology|June 26, 2017
Regulating Secretory Proteostasis through the Unfolded Protein Response: From Function to TherapyLars Plate, R Luke WisemanElife|July 21, 2016
Modulating protein quality controlLars Plate, Ryan J Paxman, R Luke Wiseman, et al.Cell Chemical Biology|May 21, 2019
Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic ProteinLars Plate, Bibiana Rius, Bianca Nguyen, et al.ACS Chemical Biology|March 2, 2019
Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation Using Targeted RNA SequencingJulia M D Grandjean, Lars Plate, Richard I Morimoto, et al.Elife|August 8, 2018
Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteinsRyan Paxman, Lars Plate, Erik A Blackwood, et al.Proceedings of the National Academy of Sciences of the United States of America|August 27, 2014
Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chainChristina B Cooley, Lisa M Ryno, Lars Plate, et al.Nature Communications|January 16, 2019
Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasisErik A Blackwood, Khalid Azizi, Donna J Thuerauf, et al.International Journal of Molecular Sciences|August 16, 2020
Premature Activation of Immune Transcription Programs in Autoimmune-Predisposed Mouse Embryonic Stem Cells and BlastocystsOktay Kirak, Eugene Ke, Kevin Y Yang, et al.Israel Journal of Chemistry|July 23, 2026
Cystic Fibrosis Modulator Therapies: Bridging Insights from CF to other Membrane Protein Misfolding DiseasesMinsoo Kim, Lars PlateThe EMBO Journal|June 29, 2017
The endoplasmic reticulum HSP40 co-chaperone ERdj3/DNAJB11 assembles and functions as a tetramerKai-Chun Chen, Song Qu, Saikat Chowdhury, et al.Pageof 20