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Frontiers in Pharmacology|April 24, 2025
A universal cannabinoid CB1 and CB2 receptor TR-FRET kinetic ligand-binding assayLeire Borrega-Roman, Bradley L Hoare, Miroslav Kosar, et al.Nature Communications|March 16, 2023
Structural basis of selective cannabinoid CB2 receptor activationXiaoting Li, Hao Chang, Jara Bouma, et al.Science Advances|February 9, 2022
Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activationTheresa Kissel, Changrong Ge, Lise Hafkenscheid, et al.Drug Discovery Today|April 17, 2017
Kinetics for Drug Discovery: an industry-driven effort to target drug residence timeDoris A Schuetz, Wilhelmus Egbertus Arnout de Witte, Yin Cheong Wong, et al.Frontiers in Pharmacology|August 27, 2021
An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of TransportersVojtech Dvorak, Tabea Wiedmer, Alvaro Ingles-Prieto, et al.Molecular Systems Biology|May 12, 2025
The solute carrier superfamily interactomeFabian Frommelt, Rene Ladurner, Ulrich Goldmann, et al.Nature Communications|January 4, 2017
Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activityMarjolein Soethoudt, Uwe Grether, Jürgen Fingerle, et al.Frontiers in Pharmacology|July 25, 2024
Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamilyDaniela Digles, Alvaro Ingles-Prieto, Vojtech Dvorak, et al.Nature Communications|December 5, 2023
A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependenceMing Jiang, Mirjam C W Huizenga, Jonah L Wirt, et al.Chimia|September 2, 2024
Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System ProjectsJohannes Aebi, Kenneth Atz, Simon M Ametamey, et al.Pageof 16