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Nature Communications|June 25, 2020
Ultra-large chemical libraries for the discovery of high-affinity peptide bindersAnthony J Quartararo, Zachary P Gates, Bente A Somsen, et al.
Journal of the American Chemical Society|February 2, 2019
Site-Directed Fragment-Based Screening for the Discovery of Protein-Protein Interaction StabilizersEline Sijbesma, Kenneth K Hallenbeck, Seppe Leysen, et al.
ACS Medicinal Chemistry Letters|June 17, 2021
Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as StabilizersEline Sijbesma, Kenneth K Hallenbeck, Sebastian A Andrei, et al.
ACS Chemical Biology|July 2, 2013
Stabilization of physical RAF/14-3-3 interaction by cotylenin A as treatment strategy for RAS mutant cancersManuela Molzan, Stefan Kasper, Lars Röglin, et al.
Journal of Medicinal Chemistry|January 29, 2016
Chiral Dihydrobenzofuran Acids Show Potent Retinoid X Receptor-Nuclear Receptor Related 1 Protein Dimer ActivationHenrik Sundén, Anja Schäfer, Marcel Scheepstra, et al.
SLAS Discovery : Advancing Life Sciences R & D|September 26, 2017
A Liquid Chromatography/Mass Spectrometry Method for Screening Disulfide Tethering FragmentsKenneth K Hallenbeck, Julia L Davies, Connie Merron, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 28, 2026
Restoring the 14-3-3/CRAF regulatory interaction in Noonan syndrome using molecular gluesJohanna M Virta, Holly R Vickery, Markella Konstantinidou, et al.
ACS Chemical Neuroscience|April 18, 2024
14-3-3τ as a Modulator of Early α-Synuclein Multimerization and Amyloid FormationGobert Heesink, Maxime C M van den Oetelaar, Slav A Semerdzhiev, et al.
Chembiochem : a European Journal of Chemical Biology|November 30, 2016
Small-Molecule-Induced and Cooperative Enzyme Assembly on a 14-3-3 ScaffoldAnniek den Hamer, Lenne J M Lemmens, Minke A D Nijenhuis, et al.
Angewandte Chemie (International Ed. in English)|December 10, 2019
A Supramolecular Stabilizer of the 14-3-3ζ/ERα Protein-Protein Interaction with a Synergistic Mode of ActionAlba Gigante, Eline Sijbesma, Pedro A Sánchez-Murcia, et al.
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