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Cell Cycle (Georgetown, Tex.)|June 4, 2010
Hsp90 phosphorylation, Wee1 and the cell cycleMehdi Mollapour, Shinji Tsutsumi, Len Neckers
Anticancer Research|May 6, 2009
Inhibition of cancer invasion and metastasis by targeting the molecular chaperone heat-shock protein 90Fumitaka Koga, Kazunori Kihara, Len Neckers
Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy|August 16, 2001
Hsp90 as an anti-cancer targetLen Neckers, Edward Mimnaugh, Theodor W. Schulte
Nature Communications|June 14, 2019
Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1Wanping Xu, Kristin Beebe, Juan D Chavez, et al.
Scientific Reports|May 5, 2018
HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulationToshiki Kijima, Thomas L Prince, Megan L Tigue, et al.
Molecular Cell|June 26, 2012
Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machineWanping Xu, Mehdi Mollapour, Chrisostomos Prodromou, et al.
Biomolecules|July 27, 2022
The Mitochondrial HSP90 Paralog TRAP1: Structural Dynamics, Interactome, Role in Metabolic Regulation, and InhibitorsAbhinav Joshi, Takeshi Ito, Didier Picard, et al.
Annals of the New York Academy of Sciences|May 22, 2007
Drugging the cancer chaperone HSP90: combinatorial therapeutic exploitation of oncogene addiction and tumor stressPaul Workman, Francis Burrows, Len Neckers, et al.
Plos One|October 31, 2015
Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted MutantsThomas L Prince, Toshiki Kijima, Manabu Tatokoro, et al.
Cancer Cell|January 29, 2013
Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethalityCarole Sourbier, Bradley T Scroggins, Ranjala Ratnayake, et al.
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