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Nature Communications|July 4, 2019
Molecular tuning of farnesoid X receptor partial agonismDaniel Merk, Sridhar Sreeramulu, Denis Kudlinzki, et al.
Chemical Science|June 30, 2023
Combining structural and coevolution information to unveil allosteric sitesGiuseppina La Sala, Christopher Pfleger, Helena Käck, et al.
Journal of Medicinal Chemistry|December 9, 2022
Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein InteractionJakob S Pallesen, Claire C Munier, Francesco Bosica, et al.
Nature Structural & Molecular Biology|February 7, 2023
Quaternary glucocorticoid receptor structure highlights allosteric interdomain communicationSandra Postel, Lisa Wissler, Carina A Johansson, et al.
Bioorganic & Medicinal Chemistry Letters|April 24, 2014
The discovery of potent and selective non-steroidal glucocorticoid receptor modulators, suitable for inhalationKarl Edman, Ragnhild Ahlgren, Malena Bengtsson, et al.
Structure (London, England : 1993)|November 26, 2015
Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary ConstraintsKarl Edman, Ali Hosseini, Magnus K Bjursell, et al.
Journal of Medicinal Chemistry|February 17, 2016
Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell SurvivalJason G Kettle, Husam Alwan, Michal Bista, et al.
Journal of Medicinal Chemistry|February 10, 2018
Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect ProfileLena Ripa, Karl Edman, Matthew Dearman, et al.
Journal of Medicinal Chemistry|March 6, 2014
Cathepsin C inhibitors: property optimization and identification of a clinical candidateMark Furber, Anna-Karin Tiden, Philip Gardiner, et al.
Journal of Medicinal Chemistry|September 23, 2017
Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary DiseasesMartin Hemmerling, Stinabritt Nilsson, Karl Edman, et al.
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