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Current Pharmaceutical Design|October 28, 2005
Progress in the discovery of BACE inhibitorsLorin A Thompson, Joanne J Bronson, F Christopher Zusi
The Journal of Organic Chemistry|March 23, 2016
Expedient Synthesis of Furo[2,3-d][1,3]thiazinamines and Pyrano[2,3-d][1,3]thiazinamines from Enones and ThioureaYong-Jin Wu, Jason Guernon, Hyunsoo Park, et al.
Bioorganic & Medicinal Chemistry Letters|February 23, 2016
Synthesis of pyrimido[4,5-c]azepine- and pyrimido[4,5-c]oxepine-based γ-secretase modulatorsYong-Jin Wu, Yunhui Zhang, Jeremy H Toyn, et al.
European Journal of Pharmacology|July 29, 2008
[3H]BMS-599240--a novel tritiated ligand for the characterization of BACE1 inhibitorsLawrence G Iben, Lisa Kopcho, Jovita Marcinkeviciene, et al.
Biochemical and Biophysical Research Communications|December 3, 2002
Mutations at the P1' position of Notch1 decrease intracellular domain stability rather than cleavage by gamma-secretaseYuval Blat, Jere E Meredith, Qian Wang, et al.
Bioorganic & Medicinal Chemistry Letters|April 21, 2009
Synthesis and SAR of hydroxyethylamine based phenylcarboxyamides as inhibitors of BACEYong-Jin Wu, Yunhui Zhang, Andrew C Good, et al.
Bioorganic & Medicinal Chemistry Letters|February 6, 2016
Design and optimization of tricyclic gamma-secretase modulatorsJianliang Shi, Dmitry Zuev, Li Xu, et al.
The Journal of Biological Chemistry|January 5, 2002
Identification and characterization of presenilin-independent Notch signalingBridget E Berechid, Magali Kitzmann, Daniel R Foltz, et al.
Bioorganic & Medicinal Chemistry Letters|November 7, 2016
Discovery of furo[2,3-d][1,3]thiazinamines as beta amyloid cleaving enzyme-1 (BACE1) inhibitorsYong-Jin Wu, Jason Guernon, Ramkumar Rajamani, et al.
Acta Crystallographica. Section F, Structural Biology Communications|March 19, 2014
The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitorSusan E Kiefer, Chiehying J Chang, S Roy Kimura, et al.
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