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Psychopharmacology Bulletin|July 25, 2009
Desvenlafaxine and venlafaxine exert minimal in vitro inhibition of human cytochrome P450 and P-glycoprotein activitiesAram Oganesian, Adam D Shilling, Ruth Young-Sciame, et al.
Drug Metabolism Letters|January 5, 2011
Comparative pharmacokinetics and metabolism studies in lean and diet- induced obese mice: an animal efficacy model for 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitorsMengmeng Wang, Xianbin Tian, Louis Leung, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 28, 2016
Clearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance MechanismsLouis Leung, Xin Yang, Timothy J Strelevitz, et al.
Chemical Research in Toxicology|September 19, 2019
Moving beyond Binary Predictions of Human Drug-Induced Liver Injury (DILI) toward Contrasting Relative Risk PotentialMichael D Aleo, Falgun Shah, Scott Allen, et al.
Bioorganic & Medicinal Chemistry Letters|February 16, 2010
Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCtheta inhibitorsDiane H Boschelli, Joan Subrath, Chuansheng Niu, et al.
Bioorganic & Medicinal Chemistry Letters|August 26, 2009
C-5 substituted heteroaryl-3-pyridinecarbonitriles as PKCtheta inhibitors: part IIAmar S Prashad, Daniel Wang, Joan Subrath, et al.
Journal of Medicinal Chemistry|February 12, 2014
Discovery of isoquinolinone indole acetic acids as antagonists of chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) for the treatment of allergic inflammatory diseasesNeelu Kaila, Bruce Follows, Louis Leung, et al.
Neuro-Degenerative Diseases|August 28, 2012
Cerebrospinal fluid β-Amyloid turnover in the mouse, dog, monkey and human evaluated by systematic quantitative analysesYasong Lu, Hugh A Barton, Louis Leung, et al.
The Journal of Pharmacology and Experimental Therapeutics|May 8, 2012
Cerebrospinal fluid amyloid-β (Aβ) as an effect biomarker for brain Aβ lowering verified by quantitative preclinical analysesYasong Lu, David Riddell, Eva Hajos-Korcsok, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 8, 2016
Evaluation of a New Molecular Entity as a Victim of Metabolic Drug-Drug Interactions-an Industry PerspectiveTonika Bohnert, Aarti Patel, Ian Templeton, et al.
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