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Nature Structural & Molecular Biology|March 23, 2004
Computational redesign of protein-protein interaction specificityTanja Kortemme, Lukasz A Joachimiak, Alex N Bullock, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 1, 2006
A Ras-induced conformational switch in the Ras activator Son of sevenlessTanya S Freedman, Holger Sondermann, Gregory D Friedland, et al.
The Journal of Cell Biology|August 25, 2010
SNX27 mediates PDZ-directed sorting from endosomes to the plasma membraneBenjamin E L Lauffer, Cristina Melero, Paul Temkin, et al.
The Journal of Physical Chemistry. B|February 6, 2018
Flex ddG: Rosetta Ensemble-Based Estimation of Changes in Protein-Protein Binding Affinity upon MutationKyle A Barlow, Shane Ó Conchúir, Samuel Thompson, et al.
Proceedings of the National Academy of Sciences of the United States of America|September 13, 2017
Engineering a light-activated caspase-3 for precise ablation of neurons in vivoAshley D Smart, Roland A Pache, Nathan D Thomsen, et al.
Chemistry & Biology|May 25, 2006
Ca2+ indicators based on computationally redesigned calmodulin-peptide pairsAmy E Palmer, Marta Giacomello, Tanja Kortemme, et al.
Science (New York, N.Y.)|August 29, 2020
Expanding the space of protein geometries by computational design of de novo fold familiesXingjie Pan, Michael C Thompson, Yang Zhang, et al.
The Journal of Biological Chemistry|August 11, 2007
Mutations designed to destabilize the receptor-bound conformation increase MICA-NKG2D association rate and affinityCandice S E Lengyel, Lindsey J Willis, Patrick Mann, et al.
Science (New York, N.Y.)|May 22, 2025
Deep learning-guided design of dynamic proteinsAmy B Guo, Deniz Akpinaroglu, Christina A Stephens, et al.
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