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Blood|October 19, 2012
The high Nrf2 expression in human acute myeloid leukemia is driven by NF-κB and underlies its chemo-resistanceStuart A Rushworth, Lyubov Zaitseva, Megan Y Murray, et al.
Scientific Reports|August 22, 2015
Targeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemiaGenevra Pillinger, Amina Abdul-Aziz, Lyubov Zaitseva, et al.
Biochemical Society Transactions|August 12, 2014
Understanding life and death decisions in human leukaemiasDavid J MacEwan, Lawrence N Barrera, Sujitra Keadsanti, et al.
Cell Cycle (Georgetown, Tex.)|January 8, 2015
Ibrutinib inhibits BTK-driven NF-κB p65 activity to overcome bortezomib-resistance in multiple myelomaMegan Y Murray, Lyubov Zaitseva, Martin J Auger, et al.
Oncotarget|October 9, 2014
Ibrutinib inhibits SDF1/CXCR4 mediated migration in AMLLyubov Zaitseva, Megan Y Murray, Manar S Shafat, et al.
Oncotarget|May 14, 2016
Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protectionGenevra Pillinger, Niamh V Loughran, Rachel E Piddock, et al.
Cancer Research|January 10, 2019
CD38-Driven Mitochondrial Trafficking Promotes Bioenergetic Plasticity in Multiple MyelomaChristopher R Marlein, Rachel E Piddock, Jayna J Mistry, et al.
Blood|July 23, 2017
NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blastsChristopher R Marlein, Lyubov Zaitseva, Rachel E Piddock, et al.
The Lancet. Haematology|December 22, 2015
Activity of Bruton's tyrosine-kinase inhibitor ibrutinib in patients with CD117-positive acute myeloid leukaemia: a mechanistic study using patient-derived blast cellsStuart A Rushworth, Genevra Pillinger, Amina Abdul-Aziz, et al.
Blood|January 5, 2017
Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironmentManar S Shafat, Thomas Oellerich, Sebastian Mohr, et al.
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