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The Journal of Biological Chemistry|March 1, 2003
Substrate-induced conformational changes in the transmembrane segments of human P-glycoprotein. Direct evidence for the substrate-induced fit mechanism for drug bindingTip W Loo, M Claire Bartlett, David M ClarkeBiochemistry|September 24, 2004
The drug-binding pocket of the human multidrug resistance P-glycoprotein is accessible to the aqueous mediumTip W Loo, M Claire Bartlett, David M ClarkeThe Journal of Biological Chemistry|November 16, 2004
The dileucine motif at the COOH terminus of human multidrug resistance P-glycoprotein is important for folding but not activityTip W Loo, M Claire Bartlett, David M ClarkeThe Journal of Biological Chemistry|December 13, 2003
Disulfide cross-linking analysis shows that transmembrane segments 5 and 8 of human P-glycoprotein are close together on the cytoplasmic side of the membraneTip W Loo, M Claire Bartlett, David M ClarkeThe Journal of Biological Chemistry|August 24, 2006
Insertion of an arginine residue into the transmembrane segments corrects protein misfoldingTip W Loo, M Claire Bartlett, David M ClarkeThe Journal of Biological Chemistry|November 8, 2002
Drug binding in human P-glycoprotein causes conformational changes in both nucleotide-binding domainsTip W Loo, M Claire Bartlett, David M ClarkeThe Journal of Biological Chemistry|June 5, 2013
Human P-glycoprotein contains a greasy ball-and-socket joint at the second transmission interfaceTip W Loo, M Claire Bartlett, David M ClarkeBiochemical Pharmacology|July 10, 2013
Corrector VX-809 stabilizes the first transmembrane domain of CFTRTip W Loo, M Claire Bartlett, David M ClarkeBiochemistry|April 28, 2011
Benzbromarone stabilizes ΔF508 CFTR at the cell surfaceTip W Loo, M Claire Bartlett, David M ClarkeThe Journal of Biological Chemistry|July 4, 2008
Arginines in the first transmembrane segment promote maturation of a P-glycoprotein processing mutant by hydrogen bond interactions with tyrosines in transmembrane segment 11Tip W Loo, M Claire Bartlett, David M ClarkePageof 5