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M Orr

Showing results (391-400 of 400) with videos related to

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Communications Chemistry|October 12, 2023
Experimental phasing opportunities for macromolecular crystallography at very long wavelengthsKamel El Omari, Ramona Duman, Vitaliy Mykhaylyk, et al.
Journal of Medicinal Chemistry|September 9, 2015
Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)Kentaro Futatsugi, Daniel W Kung, Suvi T M Orr, et al.
Bioorganic & Medicinal Chemistry Letters|August 20, 2013
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptorKim F McClure, Margaret Jackson, Kimberly O Cameron, et al.
Journal of Medicinal Chemistry|October 29, 2015
Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular DiseasesRoger B Ruggeri, Leonard Buckbinder, Scott W Bagley, et al.
Journal of Medicinal Chemistry|December 28, 2020
Structure-Based Drug Design and Synthesis of PI3Kα-Selective Inhibitor (PF-06843195)Hengmiao Cheng, Suvi T M Orr, Simon Bailey, et al.
Journal of Medicinal Chemistry|March 14, 2017
Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFRSimon Planken, Douglas C Behenna, Sajiv K Nair, et al.
Journal of Medicinal Chemistry|January 13, 2016
Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR MutantsHengmiao Cheng, Sajiv K Nair, Brion W Murray, et al.
Elife|September 11, 2015
Homo naledi, a new species of the genus Homo from the Dinaledi Chamber, South AfricaLee R Berger, John Hawks, Darryl J de Ruiter, et al.
Cancer Cell|March 11, 2025
CDK4 selective inhibition improves preclinical anti-tumor efficacy and safetyCynthia L Palmer, Britton Boras, Bernadette Pascual, et al.
Science (New York, N.Y.)|October 8, 2011
Detection of pulsed gamma rays above 100 GeV from the Crab pulsar, E Aliu, T Arlen, et al.
Pageof 40

Showing results (391-400 of 400) with videos related to

Sort By:
Pageof 40
You have reached the last page of results.This site can display upto 400 results.
Communications Chemistry|October 12, 2023
Experimental phasing opportunities for macromolecular crystallography at very long wavelengthsKamel El Omari, Ramona Duman, Vitaliy Mykhaylyk, et al.
Journal of Medicinal Chemistry|September 9, 2015
Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)Kentaro Futatsugi, Daniel W Kung, Suvi T M Orr, et al.
Bioorganic & Medicinal Chemistry Letters|August 20, 2013
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptorKim F McClure, Margaret Jackson, Kimberly O Cameron, et al.
Journal of Medicinal Chemistry|October 29, 2015
Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular DiseasesRoger B Ruggeri, Leonard Buckbinder, Scott W Bagley, et al.
Journal of Medicinal Chemistry|December 28, 2020
Structure-Based Drug Design and Synthesis of PI3Kα-Selective Inhibitor (PF-06843195)Hengmiao Cheng, Suvi T M Orr, Simon Bailey, et al.
Journal of Medicinal Chemistry|March 14, 2017
Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFRSimon Planken, Douglas C Behenna, Sajiv K Nair, et al.
Journal of Medicinal Chemistry|January 13, 2016
Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR MutantsHengmiao Cheng, Sajiv K Nair, Brion W Murray, et al.
Elife|September 11, 2015
Homo naledi, a new species of the genus Homo from the Dinaledi Chamber, South AfricaLee R Berger, John Hawks, Darryl J de Ruiter, et al.
Cancer Cell|March 11, 2025
CDK4 selective inhibition improves preclinical anti-tumor efficacy and safetyCynthia L Palmer, Britton Boras, Bernadette Pascual, et al.
Science (New York, N.Y.)|October 8, 2011
Detection of pulsed gamma rays above 100 GeV from the Crab pulsar, E Aliu, T Arlen, et al.
Pageof 40