Showing results (1-10 of 9) with videos related to
Sort By:
Pageof 1
Current Opinion in Drug Discovery & Development|February 26, 2004
Using in vitro human tissues to predict pharmacokinetic propertiesNorman D Huebert, Malini Dasgupta, Yanmin ChenRapid Communications in Mass Spectrometry : RCM|June 29, 2010
Use of stable isotope labeled probes to facilitate liquid chromatography/mass spectrometry based high-throughput screening of time-dependent CYP inhibitorsMalini Dasgupta, Weimin Tang, Gary W Caldwell, et al.Current Topics in Medicinal Chemistry|September 15, 2009
ADME optimization and toxicity assessment in early- and late-phase drug discoveryGary W Caldwell, Zhengyin Yan, Weimin Tang, et al.Biopharmaceutics & Drug Disposition|January 11, 2008
Pharmacokinetic properties of TDP4815 after single intravenous and oral administrations to rat, rabbit, monkey, dog and in vitro drug metabolismYanmin Chen, Deping Cheng, Cesar Tio, et al.Rapid Communications in Mass Spectrometry : RCM|June 3, 2008
Isobaric metabolite interferences and the requirement for close examination of raw data in addition to stringent chromatographic separations in liquid chromatography/tandem mass spectrometric analysis of drugs in biological matrixZhengyin Yan, Noureddine Maher, Rhoda Torres, et al.Bioorganic & Medicinal Chemistry Letters|April 2, 2003
Oxyguanidines: application to non-peptidic phenyl-based thrombin inhibitorsBruce Tomczuk, Tianbao Lu, Richard M Soll, et al.Journal of Medicinal Chemistry|February 18, 2005
Design, synthesis, and biological evaluation of novel potent and selective alphavbeta3/alphavbeta5 integrin dual inhibitors with improved bioavailability. Selection of the molecular coreJuan José Marugán, Carl Manthey, Beth Anaclerio, et al.Bioorganic & Medicinal Chemistry Letters|October 21, 2005
Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitorsLei Qiao, Christian A Baumann, Carl S Crysler, et al.Bioorganic & Medicinal Chemistry Letters|April 19, 2008
Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motifKevin D Kreutter, Tianbao Lu, Lily Lee, et al.Pageof 1