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Journal of Medicinal Chemistry|July 28, 2017
Nonacidic Farnesoid X Receptor ModulatorsDaniel Flesch, Sun-Yee Cheung, Jurema Schmidt, et al.Frontiers in Pharmacology|April 6, 2019
Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γTamara Göbel, Olaf Diehl, Jan Heering, et al.Journal of Medicinal Chemistry|May 2, 2020
l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARγLeonie Gellrich, Pascal Heitel, Jan Heering, et al.Biochemical Pharmacology|September 28, 2016
Characterization of the molecular mechanism of 5-lipoxygenase inhibition by 2-aminothiazolesSimon B M Kretschmer, Stefano Woltersdorf, Dominik Vogt, et al.Journal of Medicinal Chemistry|June 11, 2026
First Structure-Activity-Relationship Study of Potent G2A AntagonistsVictor Hernandez-Olmos, Jan Heering, Felix F Lillich, et al.European Journal of Medicinal Chemistry|July 28, 2018
Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E<sub>2</sub> synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammationSun-Yee Cheung, Markus Werner, Lucia Esposito, et al.Journal of Medicinal Chemistry|November 24, 2015
N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ ModulatorsRené Blöcher, Christina Lamers, Sandra K Wittmann, et al.Journal of Medicinal Chemistry|January 13, 2025
Identification of a Chemical Probe for BLT2 Activation by Scaffold HoppingVictor Hernandez-Olmos, Jan Heering, Niklas Ildefeld, et al.Journal of Medicinal Chemistry|October 12, 2020
Design, Synthesis, and Structure-Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-LipoxygenaseKerstin Hiesinger, Jan S Kramer, Sandra Beyer, et al.Journal of Medicinal Chemistry|June 25, 2024
Development of a Potent and Selective G2A (GPR132) AgonistVictor Hernandez-Olmos, Jan Heering, Beatrice Marinescu, et al.Pageof 15