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Frontiers in Molecular Biosciences|December 19, 2022
Cellular functions of the ClpP protease impacting bacterial virulenceMazen E Aljghami, Marim M Barghash, Emily Majaesic, et al.Journal of Medicinal Chemistry|September 2, 2024
Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP ProteasesFuning Lin, Mark F Mabanglo, Jin Lin Zhou, et al.Acta Neuropathologica Communications|May 11, 2021
Aβ43 aggregates exhibit enhanced prion-like seeding activity in miceAlejandro Ruiz-Riquelme, Alison Mao, Marim M Barghash, et al.ACS Infectious Diseases|November 25, 2020
Development of Antibiotics That Dysregulate the Neisserial ClpP ProteaseGursonika Binepal, Mark F Mabanglo, Jordan D Goodreid, et al.Structure (London, England : 1993)|December 31, 2022
Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminomeMark F Mabanglo, Keith S Wong, Marim M Barghash, et al.Structure (London, England : 1993)|August 12, 2025
Small molecule dysregulation of ClpP activity via bidirectional allosteric pathwaysMarim M Barghash, Mark F Mabanglo, Samuel E Hoff, et al.Communications Biology|November 23, 2019
ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance poresMark F Mabanglo, Elisa Leung, Siavash Vahidi, et al.Journal of Medicinal Chemistry|July 8, 2026
Dysregulation of Human ClpP Using Small Molecules with Piperazine-Based Scaffold for Diffuse Intrinsic Pontine Glioma Therapy Validated by Patient-Derived Tumor OrganoidsMorena Miciaccia, Domenico Armenise, Olga Maria Baldelli, et al.Pageof 1