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Biotechnology Journal|June 6, 2020
Hybrid Modeling and Intensified DoE: An Approach to Accelerate Upstream Process CharacterizationBenjamin Bayer, Gerald Striedner, Mark Duerkop
Biotechnology Journal|March 26, 2018
Impact of Cavitation, High Shear Stress and Air/Liquid Interfaces on Protein AggregationMark Duerkop, Eva Berger, Astrid Dürauer, et al.
Biotechnology Journal|November 16, 2022
Comparison of mechanistic and hybrid modeling approaches for characterization of a CHO cultivation process: Requirements, pitfalls and solution pathsBenjamin Bayer, Mark Duerkop, Ralf Pörtner, et al.
Frontiers in Bioengineering and Biotechnology|January 10, 2022
Model Transferability and Reduced Experimental Burden in Cell Culture Process Development Facilitated by Hybrid Modeling and Intensified Design of ExperimentsBenjamin Bayer, Mark Duerkop, Gerald Striedner, et al.
Scientific Reports|May 4, 2021
High shear resistance of insect cells: the basis for substantial improvements in cell culture process designFlorian Strobl, Mark Duerkop, Dieter Palmberger, et al.
Engineering in Life Sciences|April 4, 2018
Influence of cavitation and high shear stress on HSA aggregation behaviorMark Duerkop, Eva Berger, Astrid Dürauer, et al.
Biotechnology Journal|February 6, 2020
Comparison of Modeling Methods for DoE-Based Holistic Upstream Process CharacterizationBenjamin Bayer, Moritz von Stosch, Gerald Striedner, et al.
Engineering in Life Sciences|July 7, 2020
Soft sensor based on 2D-fluorescence and process data enabling real-time estimation of biomass in Escherichia coli cultivationsBenjamin Bayer, Moritz von Stosch, Michael Melcher, et al.
Biotechnology and Bioengineering|August 27, 2025
Digital Model-Driven Cell & Gene Therapy Process DevelopmentEvan Claes, Tommy Heck, Roger Dalmau-Diaz, et al.
Biotechnology Letters|November 12, 2021
Proton-transfer-reaction mass spectrometry (PTR-MS) for online monitoring of glucose depletion and cell concentrations in HEK 293 gene therapy processesBenjamin Bayer, Andreas Maccani, Johanna Jahn, et al.
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