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Methods in Enzymology|January 23, 2016
Orthogonal Methods for Characterizing the Unfolding of Therapeutic Monoclonal Antibodies: Differential Scanning Calorimetry, Isothermal Chemical Denaturation, and Intrinsic Fluorescence with Concomitant Static Light ScatteringDeniz B Temel, Pavel Landsman, Mark L BraderMolecular Pharmaceutics|June 17, 2022
A Biopharmaceutical Perspective on Higher-Order Structure and Thermal Stability of mRNA VaccinesMarek Kloczewiak, Jessica M Banks, Lin Jin, et al.ACS Omega|February 2, 2026
Consequences of mRNA Secondary Structure on Stability against both Hydrolysis and Aggregation: The Role of Electrostatic, π-π Stacking, and Thermal EffectsCurtis W Jarand, Zhiyou Deng, Mark L Brader, et al.Analytical Biochemistry|March 14, 2013
Monitoring protein aggregation kinetics with simultaneous multiple sample light scatteringMichael F Drenski, Mark L Brader, Roy W Alston, et al.Journal of Pharmaceutical Sciences|December 13, 2012
Effects of submicron particles on formation of micron-sized particles during long-term storage of an interferon-β-1a solutionShujun Bai, Yogapriya Murugesan, Milana Vlasic, et al.Journal of Pharmaceutical Sciences|June 17, 2011
Calcium binding to a factor ix Fc fusion protein and effects on higher-order structureHao Li, Shufeng Bai, Julie Y Wei, et al.Journal of Pharmaceutical Sciences|November 28, 2016
Using X-Ray Crystallography to Simplify and Accelerate Biologics Drug DevelopmentMark L Brader, Edward N Baker, Michael F Dunn, et al.Biotechnology and Bioengineering|March 16, 2011
Fragmentation of a highly purified monoclonal antibody attributed to residual CHO cell protease activitySharon X Gao, Ying Zhang, Kensey Stansberry-Perkins, et al.Biophysical Journal|March 28, 2021
Encapsulation state of messenger RNA inside lipid nanoparticlesMark L Brader, Sean J Williams, Jessica M Banks, et al.Journal of Pharmaceutical Sciences|November 1, 2005
Biophysical signatures of noncovalent aggregates formed by a glucagonlike peptide-1 analog: a prototypical example of biopharmaceutical aggregationBrandon L Doyle, Mark J Pollo, Allen H Pekar, et al.Pageof 2