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Bioorganic & Medicinal Chemistry Letters
|
November 6, 2012
Inhibition of HIV-1 capsid assembly: optimization of the antiviral potency by site selective modifications at N1, C2 and C16 of a 5-(5-furan-2-yl-pyrazol-1-yl)-1H-benzimidazole scaffold
Martin Tremblay, Pierre Bonneau, Yves Bousquet, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 3, 2013
Nucleotide competing reverse transcriptase inhibitors: discovery of a series of non-basic benzofurano[3,2-d]pyrimidin-2-one derived inhibitors
Clint A James, Patrick DeRoy, Martin Duplessis, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 16, 2013
Identification of potent and orally bioavailable nucleotide competing reverse transcriptase inhibitors: in vitro and in vivo optimization of a series of benzofurano[3,2-d]pyrimidin-2-one derived inhibitors
Claudio F Sturino, Yves Bousquet, Clint A James, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 20, 2015
Discovery, design, and synthesis of indole-based EZH2 inhibitors
Victor S Gehling, Rishi G Vaswani, Christopher G Nasveschuk, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2020
Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhibitors
Victor S Gehling, John P McGrath, Martin Duplessis, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 21, 2013
Identification of benzofurano[3,2-d]pyrimidin-2-ones, a new series of HIV-1 nucleotide-competing reverse transcriptase inhibitors
Martin Tremblay, Richard C Bethell, Michael G Cordingley, et al.
ACS Medicinal Chemistry Letters
|
May 19, 2016
Discovery of Potent, Orally Bioavailable Inhibitors of Human Cytomegalovirus
Lee Fader, Martine Brault, Jessica Desjardins, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 14, 2017
Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance
Terry D Crawford, Steffan Vartanian, Alexandre Côté, et al.
Journal of Medicinal Chemistry
|
October 15, 2016
Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas
Rishi G Vaswani, Victor S Gehling, Les A Dakin, et al.
Journal of Medicinal Chemistry
|
October 6, 2018
GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like
Shumei Wang, Vickie Tsui, Terry D Crawford, et al.
Page
of 3
Search research articles
Search
Showing results (11-20 of 24) with videos related to
Sort By:
Page
of 3
Bioorganic & Medicinal Chemistry Letters
|
November 6, 2012
Inhibition of HIV-1 capsid assembly: optimization of the antiviral potency by site selective modifications at N1, C2 and C16 of a 5-(5-furan-2-yl-pyrazol-1-yl)-1H-benzimidazole scaffold
Martin Tremblay, Pierre Bonneau, Yves Bousquet, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 3, 2013
Nucleotide competing reverse transcriptase inhibitors: discovery of a series of non-basic benzofurano[3,2-d]pyrimidin-2-one derived inhibitors
Clint A James, Patrick DeRoy, Martin Duplessis, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 16, 2013
Identification of potent and orally bioavailable nucleotide competing reverse transcriptase inhibitors: in vitro and in vivo optimization of a series of benzofurano[3,2-d]pyrimidin-2-one derived inhibitors
Claudio F Sturino, Yves Bousquet, Clint A James, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 20, 2015
Discovery, design, and synthesis of indole-based EZH2 inhibitors
Victor S Gehling, Rishi G Vaswani, Christopher G Nasveschuk, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2020
Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhibitors
Victor S Gehling, John P McGrath, Martin Duplessis, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 21, 2013
Identification of benzofurano[3,2-d]pyrimidin-2-ones, a new series of HIV-1 nucleotide-competing reverse transcriptase inhibitors
Martin Tremblay, Richard C Bethell, Michael G Cordingley, et al.
ACS Medicinal Chemistry Letters
|
May 19, 2016
Discovery of Potent, Orally Bioavailable Inhibitors of Human Cytomegalovirus
Lee Fader, Martine Brault, Jessica Desjardins, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 14, 2017
Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance
Terry D Crawford, Steffan Vartanian, Alexandre Côté, et al.
Journal of Medicinal Chemistry
|
October 15, 2016
Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas
Rishi G Vaswani, Victor S Gehling, Les A Dakin, et al.
Journal of Medicinal Chemistry
|
October 6, 2018
GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like
Shumei Wang, Vickie Tsui, Terry D Crawford, et al.
Page
of 3