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Biology|September 26, 2015
Multi-Facial, Non-Peptidic α-Helix MimeticsMaryanna E Lanning, Steven FletcherJournal of Medicinal Chemistry|October 18, 2016
Expanding the Cancer Arsenal with Targeted Therapies: Disarmament of the Antiapoptotic Bcl-2 Proteins by Small MoleculesJeremy L Yap, Lijia Chen, Maryanna E Lanning, et al.The Journal of Organic Chemistry|December 9, 2014
Chromatography-free entry to substituted salicylonitriles: Mitsunobu-triggered domino reactions of salicylaldoximesEllis Whiting, Maryanna E Lanning, Jacob A Scheenstra, et al.Chemmedchem|June 26, 2020
Rationally Designed Polypharmacology: α-Helix Mimetics as Dual Inhibitors of the Oncoproteins Mcl-1 and HDM2Ivie L Conlon, Brandon Drennen, Maryanna E Lanning, et al.Chemmedchem|February 5, 2016
Structural Re-engineering of the α-Helix Mimetic JY-1-106 into Small Molecules: Disruption of the Mcl-1-Bak-BH3 Protein-Protein Interaction with 2,6-Di-Substituted NicotinatesBrandon Drennen, Jacob A Scheenstra, Jeremy L Yap, et al.Organic Letters|June 15, 2013
Amphipathic α-helix mimetics based on a 1,2-diphenylacetylene scaffoldKwan-Young Jung, Kenno Vanommeslaeghe, Maryanna E Lanning, et al.ACS Medicinal Chemistry Letters|July 21, 2015
BRD4 Structure-Activity Relationships of Dual PLK1 Kinase/BRD4 Bromodomain Inhibitor BI-2536Lijia Chen, Jeremy L Yap, Makoto Yoshioka, et al.Journal of Medicinal Chemistry|March 4, 2015
Perturbation of the c-Myc-Max protein-protein interaction via synthetic α-helix mimeticsKwan-Young Jung, Huabo Wang, Peter Teriete, et al.Organic & Biomolecular Chemistry|April 30, 2013
Structural modifications of (Z)-3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione that improve selectivity for inhibiting the proliferation of melanoma cells containing active ERK signalingKwan-Young Jung, Ramin Samadani, Jay Chauhan, et al.European Journal of Medicinal Chemistry|March 18, 2016
Structure-based design of N-substituted 1-hydroxy-4-sulfamoyl-2-naphthoates as selective inhibitors of the Mcl-1 oncoproteinMaryanna E Lanning, Wenbo Yu, Jeremy L Yap, et al.Pageof 1