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Investigational New Drugs
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May 27, 2020
Translational approach from preclinical to clinical: comparison of dose finding methods of a new Bcl2 inhibitor using PK-PD modeling and interspecies extrapolation
Philippe B Pierrillas, Emilie Henin, Julien Ogier, et al.
Clinical Pharmacology and Therapeutics
|
March 31, 2022
How to Successfully Generate an Alternative Approach to a Thorough QT Study: GLPG1972 as an Example
Claudia Meyer, Ines Dierick, Glenn Gauderat, et al.
Pharmaceutical Research
|
June 6, 2013
Application of hematological toxicity modeling in clinical development of abexinostat (S-78454, PCI-24781), a new histone deacetylase inhibitor
Quentin Chalret du Rieu, Sylvain Fouliard, Anne Jacquet-Bescond, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
February 25, 2025
Model-Informed Drug Development of a Sustained Release Formulation of Flucytosine in the Treatment of Cryptococcal Meningitis: A Case Study Using Physiologically Based Pharmacokinetic Modeling
Johanna Eriksson, Erik Sjögren, Jean-Yves Gillon, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
April 4, 2019
Prediction of Human Nonlinear Pharmacokinetics of a New Bcl-2 Inhibitor Using PBPK Modeling and Interspecies Extrapolation Strategy
Philippe B Pierrillas, Emilie Henin, Kathryn Ball, et al.
Cancer Research Communications
|
March 27, 2023
Mechanistic Modeling of the Interplay Between Host Immune System, IL-7 and UCART19 Allogeneic CAR-T Cells in Adult B-cell Acute Lymphoblastic Leukemia
Thibaud Derippe, Sylvain Fouliard, Ibtissam Marchiq, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
February 22, 2018
Integrated Pharmacokinetic/Pharmacodynamic Model of a Bispecific CD3xCD123 DART Molecule in Nonhuman Primates: Evaluation of Activity and Impact of Immunogenicity
Olivia Campagne, Audrey Delmas, Sylvain Fouliard, et al.
Clinical Pharmacology and Therapeutics
|
January 14, 2018
Getting Innovative Therapies Faster to Patients at the Right Dose: Impact of Quantitative Pharmacology Towards First Registration and Expanding Therapeutic Use
Satyaprakash Nayak, Oliver Sander, Nidal Al-Huniti, et al.
Clinical Pharmacology and Therapeutics
|
November 12, 2019
Transforming Translation Through Quantitative Pharmacology for High-Impact Decision Making in Drug Discovery and Development
Neeraj Gupta, Dean Bottino, Ulrika S H Simonsson, et al.
European Journal of Cancer (Oxford, England : 1990)
|
June 25, 2013
Pharmacokinetic/pharmacodynamic modelling-based optimisation of administration schedule for the histone deacetylase inhibitor abexinostat (S78454/PCI-24781) in phase I
Sylvain Fouliard, Renata Robert, Anne Jacquet-Bescond, et al.
Page
of 6
Search research articles
Search
Showing results (41-50 of 57) with videos related to
Sort By:
Page
of 6
Investigational New Drugs
|
May 27, 2020
Translational approach from preclinical to clinical: comparison of dose finding methods of a new Bcl2 inhibitor using PK-PD modeling and interspecies extrapolation
Philippe B Pierrillas, Emilie Henin, Julien Ogier, et al.
Clinical Pharmacology and Therapeutics
|
March 31, 2022
How to Successfully Generate an Alternative Approach to a Thorough QT Study: GLPG1972 as an Example
Claudia Meyer, Ines Dierick, Glenn Gauderat, et al.
Pharmaceutical Research
|
June 6, 2013
Application of hematological toxicity modeling in clinical development of abexinostat (S-78454, PCI-24781), a new histone deacetylase inhibitor
Quentin Chalret du Rieu, Sylvain Fouliard, Anne Jacquet-Bescond, et al.
CPT: Pharmacometrics & Systems Pharmacology
|
February 25, 2025
Model-Informed Drug Development of a Sustained Release Formulation of Flucytosine in the Treatment of Cryptococcal Meningitis: A Case Study Using Physiologically Based Pharmacokinetic Modeling
Johanna Eriksson, Erik Sjögren, Jean-Yves Gillon, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
April 4, 2019
Prediction of Human Nonlinear Pharmacokinetics of a New Bcl-2 Inhibitor Using PBPK Modeling and Interspecies Extrapolation Strategy
Philippe B Pierrillas, Emilie Henin, Kathryn Ball, et al.
Cancer Research Communications
|
March 27, 2023
Mechanistic Modeling of the Interplay Between Host Immune System, IL-7 and UCART19 Allogeneic CAR-T Cells in Adult B-cell Acute Lymphoblastic Leukemia
Thibaud Derippe, Sylvain Fouliard, Ibtissam Marchiq, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
February 22, 2018
Integrated Pharmacokinetic/Pharmacodynamic Model of a Bispecific CD3xCD123 DART Molecule in Nonhuman Primates: Evaluation of Activity and Impact of Immunogenicity
Olivia Campagne, Audrey Delmas, Sylvain Fouliard, et al.
Clinical Pharmacology and Therapeutics
|
January 14, 2018
Getting Innovative Therapies Faster to Patients at the Right Dose: Impact of Quantitative Pharmacology Towards First Registration and Expanding Therapeutic Use
Satyaprakash Nayak, Oliver Sander, Nidal Al-Huniti, et al.
Clinical Pharmacology and Therapeutics
|
November 12, 2019
Transforming Translation Through Quantitative Pharmacology for High-Impact Decision Making in Drug Discovery and Development
Neeraj Gupta, Dean Bottino, Ulrika S H Simonsson, et al.
European Journal of Cancer (Oxford, England : 1990)
|
June 25, 2013
Pharmacokinetic/pharmacodynamic modelling-based optimisation of administration schedule for the histone deacetylase inhibitor abexinostat (S78454/PCI-24781) in phase I
Sylvain Fouliard, Renata Robert, Anne Jacquet-Bescond, et al.
Page
of 6