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Chemistry, an Asian Journal|February 13, 2009
Nazarov-type reactions in waterMasaya Kokubo, Shū KobayashiEuropean Journal of Pharmacology|October 22, 2013
Suppressive effects of a novel CC chemokine receptor 4 antagonist on Th2 cell trafficking in ligand- and antigen-induced mouse modelsTakaki Komiya, Tetsuya Sugiyama, Kazuhiko Takeda, et al.Journal of Medicinal Chemistry|July 11, 2006
Design, synthesis, and biological evaluation of the combinatorial library with a new spirodiketopiperazine scaffold. Discovery of novel potent and selective low-molecular-weight CCR5 antagonistsHiromu Habashita, Masaya Kokubo, Shin-ichi Hamano, et al.Bioorganic & Medicinal Chemistry Letters|May 11, 2019
Towards a TREK-1/2 (TWIK-Related K+ Channel 1 and 2) dual activator tool compound: Multi-dimensional optimization of BL-1249Yuzo Iwaki, Kentaro Yashiro, Masaya Kokubo, et al.Bioorganic & Medicinal Chemistry Letters|December 28, 2014
Further optimization of the M5 NAM MLPCN probe ML375: tactics and challengesHaruto Kurata, Patrick R Gentry, Masaya Kokubo, et al.ACS Chemical Neuroscience|February 21, 2025
Discovery of ONO-2920632 (VU6011887): A Highly Selective and CNS Penetrant TREK-2 (TWIK-Related K+ Channel 2) Preferring Activator <i>In Vivo</i> Tool CompoundKentaro Yashiro, Yuzo Iwaki, Hirohito Urata, et al.Journal of Medicinal Chemistry|August 23, 2014
Development of a highly potent, novel M5 positive allosteric modulator (PAM) demonstrating CNS exposure: 1-((1H-indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide (ML380)Patrick R Gentry, Masaya Kokubo, Thomas M Bridges, et al.Journal of Medicinal Chemistry|October 30, 2013
Discovery of the first M5-selective and CNS penetrant negative allosteric modulator (NAM) of a muscarinic acetylcholine receptor: (S)-9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydro-1H-imidazo[2,1-a]isoindol-5(9bH)-one (ML375)Patrick R Gentry, Masaya Kokubo, Thomas M Bridges, et al.Chemmedchem|April 3, 2014
Discovery, synthesis and characterization of a highly muscarinic acetylcholine receptor (mAChR)-selective M5-orthosteric antagonist, VU0488130 (ML381): a novel molecular probePatrick R Gentry, Masaya Kokubo, Thomas M Bridges, et al.Pageof 1