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Updated: Jun 25, 2026

Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes
05:34

Efficient Synthesis of Polyfunctionalized Benzenes in Water via Persulfate-promoted Benzannulation of α,β-Unsaturated Compounds and Alkynes

Published on: December 16, 2019

Nazarov-type reactions in water.

Masaya Kokubo1, Shū Kobayashi

  • 1Department of Chemistry, School of Science, The University of Tokyo, The HFRE Division, ERATO, JST, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Chemistry, an Asian Journal
|February 13, 2009
PubMed
Summary

Nazarov-type reactions were successfully performed in water, yielding unique products. A scandium-based catalyst exclusively produced water-trapping compounds, expanding organic synthesis in aqueous media.

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