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Journal of Medicinal Chemistry|June 23, 2007
Discovery of isonicotinamide derived beta-secretase inhibitors: in vivo reduction of beta-amyloidMatthew G Stanton, Shaun R Stauffer, Alison R Gregro, et al.
Bioorganic & Medicinal Chemistry Letters|December 17, 2009
Fluorinated piperidine acetic acids as gamma-secretase modulatorsMatthew G Stanton, Jed Hubbs, David Sloman, et al.
Bioorganic & Medicinal Chemistry Letters|January 30, 2007
Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformationShaun R Stauffer, Matthew G Stanton, Alison R Gregro, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Delayed and Prolonged Histone Hyperacetylation with a Selective HDAC1/HDAC2 InhibitorJoey L Methot, Dawn Mampreian Hoffman, David J Witter, et al.
Bioorganic & Medicinal Chemistry Letters|September 1, 2007
The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitorsChristopher L Hamblett, Joey L Methot, Dawn M Mampreian, et al.
Bioorganic & Medicinal Chemistry Letters|January 10, 2008
Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)Joey L Methot, Prasun K Chakravarty, Melissa Chenard, et al.
The Journal of Pharmacology and Experimental Therapeutics|October 16, 2008
First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman primatesSethu Sankaranarayanan, Marie A Holahan, Dennis Colussi, et al.
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