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Matthew Volgraf

Showing results (11-20 of 27) with videos related to

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Neuropharmacology|May 2, 2017
A novel NMDA receptor positive allosteric modulator that acts via the transmembrane domainTzu-Ming Wang, Brandon M Brown, Lunbin Deng, et al.
Bioorganic & Medicinal Chemistry Letters|May 1, 2014
Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitorsMatthew Volgraf, Lina Chan, Malcolm P Huestis, et al.
Neuron|February 16, 2016
Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit FunctionDavid H Hackos, Patrick J Lupardus, Teddy Grand, et al.
Neuron|May 25, 2007
Remote control of neuronal activity with a light-gated glutamate receptorStephanie Szobota, Pau Gorostiza, Filippo Del Bene, et al.
Proceedings of the National Academy of Sciences of the United States of America|December 5, 2019
TRPA1 modulation by piperidine carboxamides suggests an evolutionarily conserved binding site and gating mechanismTania Chernov-Rogan, Eleonora Gianti, Chang Liu, et al.
Elife|March 28, 2023
Cryo-EM reveals an unprecedented binding site for Na<sub>V</sub>1.7 inhibitors enabling rational design of potent hybrid inhibitorsMarc Kschonsak, Christine C Jao, Christopher P Arthur, et al.
Journal of Medicinal Chemistry|April 27, 2017
Discovery of 5-Azaindazole (GNE-955) as a Potent Pan-Pim Inhibitor with Optimized BioavailabilityXiaojing Wang, Aleksandr Kolesnikov, Suzanne Tay, et al.
Neuron|November 5, 2020
A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion ChannelChang Liu, Rebecca Reese, Simon Vu, et al.
Journal of Medicinal Chemistry|March 12, 2024
Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte FormationRuth Dorel, Dawei Sun, Nicholas Carruthers, et al.
ACS Medicinal Chemistry Letters|January 21, 2017
GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved <i>in Vivo</i> ProfileElisia Villemure, Matthew Volgraf, Yu Jiang, et al.
Pageof 3

Showing results (11-20 of 27) with videos related to

Sort By:
Pageof 3
Neuropharmacology|May 2, 2017
A novel NMDA receptor positive allosteric modulator that acts via the transmembrane domainTzu-Ming Wang, Brandon M Brown, Lunbin Deng, et al.
Bioorganic & Medicinal Chemistry Letters|May 1, 2014
Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitorsMatthew Volgraf, Lina Chan, Malcolm P Huestis, et al.
Neuron|February 16, 2016
Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit FunctionDavid H Hackos, Patrick J Lupardus, Teddy Grand, et al.
Neuron|May 25, 2007
Remote control of neuronal activity with a light-gated glutamate receptorStephanie Szobota, Pau Gorostiza, Filippo Del Bene, et al.
Proceedings of the National Academy of Sciences of the United States of America|December 5, 2019
TRPA1 modulation by piperidine carboxamides suggests an evolutionarily conserved binding site and gating mechanismTania Chernov-Rogan, Eleonora Gianti, Chang Liu, et al.
Elife|March 28, 2023
Cryo-EM reveals an unprecedented binding site for Na<sub>V</sub>1.7 inhibitors enabling rational design of potent hybrid inhibitorsMarc Kschonsak, Christine C Jao, Christopher P Arthur, et al.
Journal of Medicinal Chemistry|April 27, 2017
Discovery of 5-Azaindazole (GNE-955) as a Potent Pan-Pim Inhibitor with Optimized BioavailabilityXiaojing Wang, Aleksandr Kolesnikov, Suzanne Tay, et al.
Neuron|November 5, 2020
A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion ChannelChang Liu, Rebecca Reese, Simon Vu, et al.
Journal of Medicinal Chemistry|March 12, 2024
Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte FormationRuth Dorel, Dawei Sun, Nicholas Carruthers, et al.
ACS Medicinal Chemistry Letters|January 21, 2017
GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved <i>in Vivo</i> ProfileElisia Villemure, Matthew Volgraf, Yu Jiang, et al.
Pageof 3