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Meihua Tu

Showing results (31-40 of 41) with videos related to

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Journal of the American Chemical Society|February 24, 2017
Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein ReceptorCarlos A Sanhueza, Michael M Baksh, Benjamin Thuma, et al.
Journal of Medicinal Chemistry|December 14, 2011
Maximizing lipophilic efficiency: the use of Free-Wilson analysis in the design of inhibitors of acetyl-CoA carboxylaseKevin D Freeman-Cook, Paul Amor, Scott Bader, et al.
Bioorganic & Medicinal Chemistry Letters|October 24, 2012
The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of type 2 diabetes mellitusJeffrey A Pfefferkorn, Meihua Tu, Kevin J Filipski, et al.
Journal of the American Chemical Society|April 19, 2018
Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene EditingRomain Rouet, Benjamin A Thuma, Marc D Roy, et al.
Journal of Medicinal Chemistry|September 10, 2020
Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of FructoseKentaro Futatsugi, Aaron C Smith, Meihua Tu, et al.
Bioorganic & Medicinal Chemistry Letters|August 20, 2013
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptorKim F McClure, Margaret Jackson, Kimberly O Cameron, et al.
Journal of Medicinal Chemistry|August 5, 2016
Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic NephropathyKimberly O Cameron, Daniel W Kung, Amit S Kalgutkar, et al.
Journal of Medicinal Chemistry|August 31, 2017
Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK)Kim Huard, Kay Ahn, Paul Amor, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 27, 2004
The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: evaluation using the MDR1A/1B knockout mouse modelAngela Doran, R Scott Obach, Bill J Smith, et al.
Journal of Medicinal Chemistry|February 22, 2018
Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK)David J Edmonds, Daniel W Kung, Amit S Kalgutkar, et al.
Pageof 5

Showing results (31-40 of 41) with videos related to

Sort By:
Pageof 5
Journal of the American Chemical Society|February 24, 2017
Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein ReceptorCarlos A Sanhueza, Michael M Baksh, Benjamin Thuma, et al.
Journal of Medicinal Chemistry|December 14, 2011
Maximizing lipophilic efficiency: the use of Free-Wilson analysis in the design of inhibitors of acetyl-CoA carboxylaseKevin D Freeman-Cook, Paul Amor, Scott Bader, et al.
Bioorganic & Medicinal Chemistry Letters|October 24, 2012
The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of type 2 diabetes mellitusJeffrey A Pfefferkorn, Meihua Tu, Kevin J Filipski, et al.
Journal of the American Chemical Society|April 19, 2018
Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene EditingRomain Rouet, Benjamin A Thuma, Marc D Roy, et al.
Journal of Medicinal Chemistry|September 10, 2020
Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of FructoseKentaro Futatsugi, Aaron C Smith, Meihua Tu, et al.
Bioorganic & Medicinal Chemistry Letters|August 20, 2013
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptorKim F McClure, Margaret Jackson, Kimberly O Cameron, et al.
Journal of Medicinal Chemistry|August 5, 2016
Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic NephropathyKimberly O Cameron, Daniel W Kung, Amit S Kalgutkar, et al.
Journal of Medicinal Chemistry|August 31, 2017
Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK)Kim Huard, Kay Ahn, Paul Amor, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 27, 2004
The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: evaluation using the MDR1A/1B knockout mouse modelAngela Doran, R Scott Obach, Bill J Smith, et al.
Journal of Medicinal Chemistry|February 22, 2018
Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK)David J Edmonds, Daniel W Kung, Amit S Kalgutkar, et al.
Pageof 5