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American Journal of Physiology. Cell Physiology|June 13, 2003
Functional role of the NPxxY motif in internalization of the type 2 vasopressin receptor in LLC-PK1 cellsRichard Bouley, Tian-Xiao Sun, Melissa Chenard, et al.Bioorganic & Medicinal Chemistry Letters|December 7, 2007
Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2)David J Witter, Paul Harrington, Kevin J Wilson, et al.Neoplasia (New York, N.Y.)|December 25, 2008
A quantitative volumetric micro-computed tomography method to analyze lung tumors in genetically engineered mouse modelsBrian B Haines, Kimberly A Bettano, Melissa Chenard, et al.Biochemistry|January 24, 2014
Divergent kinetics differentiate the mechanism of action of two HDAC inhibitorsAstrid M Kral, Nicole Ozerova, Joshua Close, et al.BMC Medical Genomics|July 2, 2010
A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumorsAndrey Loboda, Michael Nebozhyn, Rich Klinghoffer, et al.Molecular Cancer Therapeutics|March 18, 2016
An Unbiased Oncology Compound Screen to Identify Novel Combination StrategiesJennifer O'Neil, Yair Benita, Igor Feldman, et al.Bioorganic & Medicinal Chemistry Letters|February 29, 2008
Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1)Kevin J Wilson, David J Witter, Jonathan B Grimm, et al.Bioorganic & Medicinal Chemistry Letters|March 10, 2009
Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2)Richard W Heidebrecht, Melissa Chenard, Joshua Close, et al.Bioorganic & Medicinal Chemistry Letters|October 28, 2008
SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2)Joey L Methot, Christopher L Hamblett, Dawn M Mampreian, et al.Bioorganic & Medicinal Chemistry Letters|January 14, 2009
Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimizationSolomon D Kattar, Laura M Surdi, Anna Zabierek, et al.Pageof 2