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The Journal of Clinical Investigation|July 26, 2011
Shock and awe: unleashing the heat shock response to treat Huntington diseaseMeredith E Jackrel, James ShorterFrontiers in Neuroscience|March 16, 2017
Protein-Remodeling Factors As Potential Therapeutics for Neurodegenerative DiseaseMeredith E Jackrel, James ShorterPrion|March 5, 2015
Engineering enhanced protein disaggregases for neurodegenerative diseaseMeredith E Jackrel, James ShorterCell Cycle (Georgetown, Tex.)|April 4, 2014
Reversing deleterious protein aggregation with re-engineered protein disaggregasesMeredith E Jackrel, James ShorterDisease Models & Mechanisms|July 27, 2014
Potentiated Hsp104 variants suppress toxicity of diverse neurodegenerative disease-linked proteinsMeredith E Jackrel, James ShorterJournal of Visualized Experiments : Jove|November 20, 2014
Isolating potentiated Hsp104 variants using yeast proteinopathy modelsMeredith E Jackrel, Amber Tariq, Keolamau Yee, et al.ACS Chemical Biology|October 7, 2015
Disparate Mutations Confer Therapeutic Gain of Hsp104 FunctionMeredith E Jackrel, Keolamau Yee, Amber Tariq, et al.The Journal of Biological Chemistry|June 8, 2019
Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcomaJeremy J Ryan, Macy L Sprunger, Kayla Holthaus, et al.The Journal of Cell Biology|March 17, 2017
FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosinationKyota Yasuda, Sarah F Clatterbuck-Soper, Meredith E Jackrel, et al.The Journal of Biological Chemistry|January 10, 2016
Mechanistic Insights into Hsp104 PotentiationMariana P Torrente, Edward Chuang, Megan M Noll, et al.Pageof 21