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Cell|July 19, 2014
γ-Secretase: a horseshoe structure brings good luckMichael S Wolfe, Dennis J Selkoe
Cell|October 25, 2007
Presenilin: running with scissors in the membraneDennis J Selkoe, Michael S Wolfe
Cell|July 27, 2010
Giving Alzheimer's the old one-twoMichael S Wolfe, Dennis J Selkoe
Structure (London, England : 1993)|March 13, 2009
Toward structural elucidation of the gamma-secretase complexHuilin Li, Michael S Wolfe, Dennis J Selkoe
Biochemistry|June 19, 2014
Pen-2 is essential for γ-secretase complex stability and trafficking but partially dispensable for endoproteolysisOliver Holmes, Swetha Paturi, Dennis J Selkoe, et al.
Journal of Neurochemistry|May 29, 2014
Functional analysis and purification of a Pen-2 fusion protein for γ-secretase structural studiesOliver Holmes, Swetha Paturi, Michael S Wolfe, et al.
The Journal of Biological Chemistry|February 11, 2021
Hydrophilic loop 1 of Presenilin-1 and the APP GxxxG transmembrane motif regulate γ-secretase function in generating Alzheimer-causing Aβ peptidesLei Liu, Bianca M Lauro, Michael S Wolfe, et al.
The Journal of Biological Chemistry|June 10, 2008
Direct and potent regulation of gamma-secretase by its lipid microenvironmentPamela Osenkowski, Wenjuan Ye, Rong Wang, et al.
Biochemistry|April 12, 2012
Effects of membrane lipids on the activity and processivity of purified γ-secretaseOliver Holmes, Swetha Paturi, Wenjuan Ye, et al.
The Journal of Cell Biology|January 11, 2019
A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursorLei Liu, Li Ding, Matteo Rovere, et al.
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