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ACS Chemical Biology
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June 3, 2015
Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4
Michael Zengerle, Kwok-Ho Chan, Alessio Ciulli
Journal of Medicinal Chemistry
|
June 9, 2017
Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds
Kwok-Ho Chan, Michael Zengerle, Andrea Testa, et al.
Toxicology Letters
|
November 5, 2013
Detoxification of alkyl methylphosphonofluoridates by an oxime-substituted β-cyclodextrin--an in vitro structure-activity study
Anne Bierwisch, Michael Zengerle, Horst Thiermann, et al.
Current Opinion in Chemical Biology
|
July 17, 2016
Chemical genetics approaches for selective intervention in epigenetics
Andrew C Runcie, Kwok-Ho Chan, Michael Zengerle, et al.
Toxicology Letters
|
February 25, 2014
Effectiveness of a substituted β-cyclodextrin to prevent cyclosarin toxicity in vivo
Franz Worek, Thomas Seeger, Michael Zengerle, et al.
Beilstein Journal of Organic Chemistry
|
January 13, 2012
Highly efficient cyclosarin degradation mediated by a β-cyclodextrin derivative containing an oxime-derived substituent
Michael Zengerle, Florian Brandhuber, Christian Schneider, et al.
Journal of Medicinal Chemistry
|
September 15, 2015
New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain Inhibition
Matthias G J Baud, Enrique Lin-Shiao, Michael Zengerle, et al.
Chemical Communications (Cambridge, England)
|
March 19, 2013
Tabun scavengers based on hydroxamic acid containing cyclodextrins
Florian Brandhuber, Michael Zengerle, Luzian Porwol, et al.
Toxicology
|
September 18, 2012
Detoxification of tabun at physiological pH mediated by substituted β-cyclodextrin and glucose derivatives containing oxime groups
Florian Brandhuber, Michael Zengerle, Luzian Porwol, et al.
Nature Chemical Biology
|
March 14, 2017
Structural basis of PROTAC cooperative recognition for selective protein degradation
Morgan S Gadd, Andrea Testa, Xavier Lucas, et al.
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Search research articles
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Showing results (1-10 of 13) with videos related to
Sort By:
Page
of 2
ACS Chemical Biology
|
June 3, 2015
Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4
Michael Zengerle, Kwok-Ho Chan, Alessio Ciulli
Journal of Medicinal Chemistry
|
June 9, 2017
Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds
Kwok-Ho Chan, Michael Zengerle, Andrea Testa, et al.
Toxicology Letters
|
November 5, 2013
Detoxification of alkyl methylphosphonofluoridates by an oxime-substituted β-cyclodextrin--an in vitro structure-activity study
Anne Bierwisch, Michael Zengerle, Horst Thiermann, et al.
Current Opinion in Chemical Biology
|
July 17, 2016
Chemical genetics approaches for selective intervention in epigenetics
Andrew C Runcie, Kwok-Ho Chan, Michael Zengerle, et al.
Toxicology Letters
|
February 25, 2014
Effectiveness of a substituted β-cyclodextrin to prevent cyclosarin toxicity in vivo
Franz Worek, Thomas Seeger, Michael Zengerle, et al.
Beilstein Journal of Organic Chemistry
|
January 13, 2012
Highly efficient cyclosarin degradation mediated by a β-cyclodextrin derivative containing an oxime-derived substituent
Michael Zengerle, Florian Brandhuber, Christian Schneider, et al.
Journal of Medicinal Chemistry
|
September 15, 2015
New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain Inhibition
Matthias G J Baud, Enrique Lin-Shiao, Michael Zengerle, et al.
Chemical Communications (Cambridge, England)
|
March 19, 2013
Tabun scavengers based on hydroxamic acid containing cyclodextrins
Florian Brandhuber, Michael Zengerle, Luzian Porwol, et al.
Toxicology
|
September 18, 2012
Detoxification of tabun at physiological pH mediated by substituted β-cyclodextrin and glucose derivatives containing oxime groups
Florian Brandhuber, Michael Zengerle, Luzian Porwol, et al.
Nature Chemical Biology
|
March 14, 2017
Structural basis of PROTAC cooperative recognition for selective protein degradation
Morgan S Gadd, Andrea Testa, Xavier Lucas, et al.
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of 2