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Frontiers in Chemistry
|
November 11, 2020
Sensitive LC-MS/MS Method for the Quantification of Macrocyclic Gα<sub>q</sub> Protein Inhibitors in Biological Samples
Markus Kuschak, Jonathan G Schlegel, Marion Schneider, et al.
ACS Pharmacology & Translational Science
|
April 16, 2021
Macrocyclic Gq Protein Inhibitors FR900359 and/or YM-254890-Fit for Translation?
Jonathan G Schlegel, Mariam Tahoun, Alexander Seidinger, et al.
Science Translational Medicine
|
September 15, 2017
Targeted inhibition of G<sub>q</sub> signaling induces airway relaxation in mouse models of asthma
Michaela Matthey, Richard Roberts, Alexander Seidinger, et al.
EMBO Molecular Medicine
|
July 8, 2024
Pharmacological Gq inhibition induces strong pulmonary vasorelaxation and reverses pulmonary hypertension
Alexander Seidinger, Richard Roberts, Yan Bai, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 9, 2026
Beta arrestin 1 is a key regulator of pulmonary vascular tone
Leonard F Lebender, Alexander Seidinger, Michaela Matthey, et al.
Basic Research in Cardiology
|
July 2, 2014
The endocannabinoid-CB2 receptor axis protects the ischemic heart at the early stage of cardiomyopathy
Georg D Duerr, Jan C Heinemann, Georg Suchan, et al.
British Journal of Pharmacology
|
December 28, 2019
Cell-permeable high-affinity tracers for G<sub>q</sub> proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors
Markus Kuschak, Vigneshwaran Namasivayam, Muhammad Rafehi, et al.
Plos One
|
December 15, 2010
O-glycosylation regulates ubiquitination and degradation of the anti-inflammatory protein A20 to accelerate atherosclerosis in diabetic ApoE-null mice
Gautam V Shrikhande, Salvatore T Scali, Cleide G da Silva, et al.
Signal Transduction and Targeted Therapy
|
April 20, 2025
Subnanomolar MAS-related G protein-coupled receptor-X2/B2 antagonists with efficacy in human mast cells and disease models
Ghazl Al Hamwi, Mohamad Wessam Alnouri, Sven Verdonck, et al.
Molecular Cell
|
November 17, 2020
Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs
Eva Marie Pfeil, Julian Brands, Nicole Merten, et al.
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of 3
Search research articles
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Showing results (11-20 of 21) with videos related to
Sort By:
Page
of 3
Frontiers in Chemistry
|
November 11, 2020
Sensitive LC-MS/MS Method for the Quantification of Macrocyclic Gα<sub>q</sub> Protein Inhibitors in Biological Samples
Markus Kuschak, Jonathan G Schlegel, Marion Schneider, et al.
ACS Pharmacology & Translational Science
|
April 16, 2021
Macrocyclic Gq Protein Inhibitors FR900359 and/or YM-254890-Fit for Translation?
Jonathan G Schlegel, Mariam Tahoun, Alexander Seidinger, et al.
Science Translational Medicine
|
September 15, 2017
Targeted inhibition of G<sub>q</sub> signaling induces airway relaxation in mouse models of asthma
Michaela Matthey, Richard Roberts, Alexander Seidinger, et al.
EMBO Molecular Medicine
|
July 8, 2024
Pharmacological Gq inhibition induces strong pulmonary vasorelaxation and reverses pulmonary hypertension
Alexander Seidinger, Richard Roberts, Yan Bai, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 9, 2026
Beta arrestin 1 is a key regulator of pulmonary vascular tone
Leonard F Lebender, Alexander Seidinger, Michaela Matthey, et al.
Basic Research in Cardiology
|
July 2, 2014
The endocannabinoid-CB2 receptor axis protects the ischemic heart at the early stage of cardiomyopathy
Georg D Duerr, Jan C Heinemann, Georg Suchan, et al.
British Journal of Pharmacology
|
December 28, 2019
Cell-permeable high-affinity tracers for G<sub>q</sub> proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors
Markus Kuschak, Vigneshwaran Namasivayam, Muhammad Rafehi, et al.
Plos One
|
December 15, 2010
O-glycosylation regulates ubiquitination and degradation of the anti-inflammatory protein A20 to accelerate atherosclerosis in diabetic ApoE-null mice
Gautam V Shrikhande, Salvatore T Scali, Cleide G da Silva, et al.
Signal Transduction and Targeted Therapy
|
April 20, 2025
Subnanomolar MAS-related G protein-coupled receptor-X2/B2 antagonists with efficacy in human mast cells and disease models
Ghazl Al Hamwi, Mohamad Wessam Alnouri, Sven Verdonck, et al.
Molecular Cell
|
November 17, 2020
Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs
Eva Marie Pfeil, Julian Brands, Nicole Merten, et al.
Page
of 3