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Nature Medicine|October 16, 2025
Obesity due to MC4R deficiency is associated with reduced cholesterol, triglycerides and cardiovascular disease riskStefanie Zorn, Rebecca Bounds, Alice Williamson, et al.
Biorxiv : the Preprint Server for Biology|August 16, 2024
Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapyAliki Perdikari, Virgil A Woods, Ali Ebrahim, et al.
The Journal of Biological Chemistry|October 24, 2025
Structures of human protein tyrosine phosphatase variants reveal targetable allosteric sitesAliki Perdikari, Virgil A Woods, Ali Ebrahim, et al.
The Journal of Clinical Endocrinology and Metabolism|February 9, 2022
Obesity Due to Steroid Receptor Coactivator-1 Deficiency Is Associated With Endocrine and Metabolic AbnormalitiesTessa M Cacciottolo, Elana Henning, Julia M Keogh, et al.
Diabetes|August 25, 2025
Glucagon Receptor Deficiency Causes Early-Onset Hepatic SteatosisTessa M Cacciottolo, Katherine Lawler, Kevin M Méndez-Acevedo, et al.
Nature Methods|April 28, 2015
G&T-seq: parallel sequencing of single-cell genomes and transcriptomesIain C Macaulay, Wilfried Haerty, Parveen Kumar, et al.
Nature Medicine|May 11, 2023
Accelerated waning of the humoral response to COVID-19 vaccines in obesityAgatha A van der Klaauw, Emily C Horner, Pehuén Pereyra-Gerber, et al.
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