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Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 29, 2011
A semiphysiologically based pharmacokinetic modeling approach to predict the dose-exposure relationship of an antiparasitic prodrug/active metabolite pairGrace Zhixia Yan, Claudia N Generaux, Miyoung Yoon, et al.
CPT: Pharmacometrics & Systems Pharmacology|January 11, 2023
Regulatory utility of mechanistic modeling to support alternative bioequivalence approaches: A workshop overviewAndrew Babiskin, Fang Wu, Youssef Mousa, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|August 8, 2020
Kinetics of metabolism of deltamethrin and <i>cis</i>- and <i>trans</i>-permethrin <i>in vitro</i>. Studies using rat and human liver microsomes, isolated rat hepatocytes and rat liver cytosolRoger J Price, Mary P Scott, Carina Cantrill, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|May 19, 2020
Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With PyrethroidsPankajini Mallick, Gina Song, Alina Y Efremenko, et al.
Frontiers in Pharmacology|October 24, 2022
Estimating provisional margins of exposure for data-poor chemicals using high-throughput computational methodsChantel I Nicolas, Matthew W Linakis, Melyssa S Minto, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|February 16, 2019
Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to In Vivo ExtrapolationGina Song, Marjory Moreau, Alina Efremenko, et al.
Frontiers in Toxicology|May 16, 2022
Considerations for Improving Metabolism Predictions for <i>In Vitro</i> to <i>In Vivo</i> ExtrapolationMarjory Moreau, Pankajini Mallick, Marci Smeltz, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|October 9, 2019
Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in HumansPankajini Mallick, Marjory Moreau, Gina Song, et al.
Toxicology in Vitro : an International Journal Published in Association with BIBRA|April 12, 2020
Application of a combined aggregate exposure pathway and adverse outcome pathway (AEP-AOP) approach to inform a cumulative risk assessment: A case study with phthalatesRebecca A Clewell, Jeremy A Leonard, Chantel I Nicolas, et al.
Toxicology in Vitro : an International Journal Published in Association with BIBRA|February 3, 2018
Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assaysPatrick D McMullen, Melvin E Andersen, Brian Cholewa, et al.
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