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Plos One
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June 30, 2015
Serendipitous SAD Solution for DMSO-Soaked SOCS2-ElonginC-ElonginB Crystals Using Covalently Incorporated Dimethylarsenic: Insights into Substrate Receptor Conformational Flexibility in Cullin RING Ligases
Morgan S Gadd, Emil Bulatov, Alessio Ciulli
Structure (London, England : 1993)
|
June 8, 2017
Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex
Teresa A F Cardote, Morgan S Gadd, Alessio Ciulli
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
November 13, 2012
Crystallization and diffraction of an Isl1-Ldb1 complex
Morgan S Gadd, David A Jacques, J Mitchell Guss, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 1, 2022
Selective Wee1 degradation by PROTAC degraders recruiting VHL and CRBN E3 ubiquitin ligases
Marine C Aublette, Tom A Harrison, Elizabeth J Thorpe, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
February 6, 2009
Crystallization and diffraction of an Lhx4-Isl2 complex
Morgan S Gadd, David B Langley, J Mitchell Guss, et al.
The Journal of Biological Chemistry
|
October 26, 2011
Structural basis for partial redundancy in a class of transcription factors, the LIM homeodomain proteins, in neural cell type specification
Morgan S Gadd, Mugdha Bhati, Cy M Jeffries, et al.
Nature Chemical Biology
|
March 14, 2017
Structural basis of PROTAC cooperative recognition for selective protein degradation
Morgan S Gadd, Andrea Testa, Xavier Lucas, et al.
The Journal of Biological Chemistry
|
June 11, 2013
A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions
Morgan S Gadd, David A Jacques, Ivan Nisevic, et al.
Journal of Medicinal Chemistry
|
August 31, 2017
Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Structure-Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298)
Pedro Soares, Morgan S Gadd, Julianty Frost, et al.
Journal of Medicinal Chemistry
|
August 29, 2014
Structure-guided design and optimization of small molecules targeting the protein-protein interaction between the von Hippel-Lindau (VHL) E3 ubiquitin ligase and the hypoxia inducible factor (HIF) alpha subunit with in vitro nanomolar affinities
Carles Galdeano, Morgan S Gadd, Pedro Soares, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 15) with videos related to
Sort By:
Page
of 2
Plos One
|
June 30, 2015
Serendipitous SAD Solution for DMSO-Soaked SOCS2-ElonginC-ElonginB Crystals Using Covalently Incorporated Dimethylarsenic: Insights into Substrate Receptor Conformational Flexibility in Cullin RING Ligases
Morgan S Gadd, Emil Bulatov, Alessio Ciulli
Structure (London, England : 1993)
|
June 8, 2017
Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex
Teresa A F Cardote, Morgan S Gadd, Alessio Ciulli
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
November 13, 2012
Crystallization and diffraction of an Isl1-Ldb1 complex
Morgan S Gadd, David A Jacques, J Mitchell Guss, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 1, 2022
Selective Wee1 degradation by PROTAC degraders recruiting VHL and CRBN E3 ubiquitin ligases
Marine C Aublette, Tom A Harrison, Elizabeth J Thorpe, et al.
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|
February 6, 2009
Crystallization and diffraction of an Lhx4-Isl2 complex
Morgan S Gadd, David B Langley, J Mitchell Guss, et al.
The Journal of Biological Chemistry
|
October 26, 2011
Structural basis for partial redundancy in a class of transcription factors, the LIM homeodomain proteins, in neural cell type specification
Morgan S Gadd, Mugdha Bhati, Cy M Jeffries, et al.
Nature Chemical Biology
|
March 14, 2017
Structural basis of PROTAC cooperative recognition for selective protein degradation
Morgan S Gadd, Andrea Testa, Xavier Lucas, et al.
The Journal of Biological Chemistry
|
June 11, 2013
A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions
Morgan S Gadd, David A Jacques, Ivan Nisevic, et al.
Journal of Medicinal Chemistry
|
August 31, 2017
Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Structure-Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298)
Pedro Soares, Morgan S Gadd, Julianty Frost, et al.
Journal of Medicinal Chemistry
|
August 29, 2014
Structure-guided design and optimization of small molecules targeting the protein-protein interaction between the von Hippel-Lindau (VHL) E3 ubiquitin ligase and the hypoxia inducible factor (HIF) alpha subunit with in vitro nanomolar affinities
Carles Galdeano, Morgan S Gadd, Pedro Soares, et al.
Page
of 2