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Scientific Reports|April 20, 2024
Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementiaZachary C Rosenthal, Daniel M Fass, N Connor Payne, et al.Nature Communications|August 25, 2022
Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistanceMark A Tye, N Connor Payne, Catrine Johansson, et al.Advanced Materials (Deerfield Beach, Fla.)|January 19, 2024
Inhibiting the Keap1/Nrf2 Protein-Protein Interaction with Protein-Like PolymersKendal P Carrow, Haylee L Hamilton, Madeline P Hopps, et al.Nature Chemical Biology|May 28, 2026
Pharmacological targeting of IRF4 as a therapeutic strategy for multiple myelomaMichael P Agius, Chen Song, Qi Liu, et al.Biorxiv : the Preprint Server for Biology|May 27, 2024
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor ComplexesXiaowen Xie, Olivia Zhang, Megan J R Yeo, et al.Nature|February 12, 2025
Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutationsXiaowen Xie, Olivia Zhang, Megan J R Yeo, et al.Cell Reports Methods|April 14, 2023
Diagnostic TR-FRET assays for detection of antibodies in patient samplesHong Yue, Radosław P Nowak, Daan Overwijn, et al.Blood Cancer Journal|January 11, 2023
Prolyl-tRNA synthetase as a novel therapeutic target in multiple myelomaKeiji Kurata, Anna James-Bott, Mark A Tye, et al.Biorxiv : the Preprint Server for Biology|July 15, 2025
Phosphorylation-inducing chimera rewires oncogenic kinase to trigger apoptosisManuel L Merz, Veronika M Shoba, Rajaiah Pergu, et al.ACS Central Science|April 27, 2026
Proximity-Induced Rewiring of Oncogenic Kinase Triggers ApoptosisManuel L Merz, Veronika M Shoba, Rajaiah Pergu, et al.Pageof 6