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Cancer Discovery|April 22, 2021
Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in CancerClare F Malone, Neekesh V Dharia, Guillaume Kugener, et al.Molecular Cancer Therapeutics|December 9, 2024
KT-253, a Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy than MDM2 Small-Molecule InhibitorsYogesh K Chutake, Michele F Mayo, Nancy Dumont, et al.Cancer Discovery|December 28, 2022
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in CarcinomasLisa D Cervia, Tsukasa Shibue, Ashir A Borah, et al.Nature Biomedical Engineering|April 7, 2019
Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse modelsWalid S Kamoun, Dmitri B Kirpotin, Zhaohua Richard Huang, et al.Cell Reports|October 3, 2019
Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven CancersRita Sulahian, Jason J Kwon, Katherine H Walsh, et al.Nature Cancer|April 19, 2022
Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancerDaniel P Bondeson, Brenton R Paolella, Adhana Asfaw, et al.Cell Reports|December 16, 2020
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16qJasper E Neggers, Brenton R Paolella, Adhana Asfaw, et al.Nature Cancer|July 3, 2020
Discovering the anti-cancer potential of non-oncology drugs by systematic viability profilingSteven M Corsello, Rohith T Nagari, Ryan D Spangler, et al.Nature|April 12, 2019
WRN helicase is a synthetic lethal target in microsatellite unstable cancersEdmond M Chan, Tsukasa Shibue, James M McFarland, et al.Pageof 3