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Journal of Medicinal Chemistry|March 22, 2023
Structure-Based Design of Y-Shaped Covalent TEAD InhibitorsWenchao Lu, Mengyang Fan, Wenzhi Ji, et al.Nature Chemical Biology|August 30, 2016
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitorsTinghu Zhang, Nicholas Kwiatkowski, Calla M Olson, et al.Cancer Research|December 21, 2017
ER Stress Signaling Promotes the Survival of Cancer "Persister Cells" Tolerant to EGFR Tyrosine Kinase InhibitorsHideki Terai, Shunsuke Kitajima, Danielle S Potter, et al.Cancer Cell|February 14, 2018
Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating MutationsRinath Jeselsohn, Johann S Bergholz, Matthew Pun, et al.Science Advances|September 12, 2020
CDK13 cooperates with CDK12 to control global RNA polymerase II processivityZheng Fan, Jennifer R Devlin, Simon J Hogg, et al.Nature|July 22, 2014
Targeting transcription regulation in cancer with a covalent CDK7 inhibitorNicholas Kwiatkowski, Tinghu Zhang, Peter B Rahl, et al.Journal of the National Cancer Institute|August 14, 2013
Effects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugsBakhos A Tannous, Mariam Kerami, Petra M Van der Stoop, et al.Cancer Cell|December 10, 2014
Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitorCamilla L Christensen, Nicholas Kwiatkowski, Brian J Abraham, et al.Cancer Discovery|October 22, 2017
Suppression of Adaptive Responses to Targeted Cancer Therapy by Transcriptional RepressionMaria Rusan, Kapsok Li, Yvonne Li, et al.Cancer Cell|December 30, 2019
CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung CancerHua Zhang, Camilla L Christensen, Ruben Dries, et al.Pageof 4