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Cancer Biology & Therapy|January 17, 2004
The Tyr-kinase inhibitor AG879, that blocks the ETK-PAK1 interaction, suppresses the RAS-induced PAK1 activation and malignant transformationHong He, Yumiko Hirokawa, Aviv Gazit, et al.Bioorganic & Medicinal Chemistry Letters|January 24, 2021
Development of an automated assay for accelerated in vitro detection of DNA adduct-inducing and crosslinking agentsJelena Medan, Brad E Sleebs, Kurt Lackovic, et al.Cell Death and Differentiation|October 1, 2016
Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIMLeona Rohrbeck, Jia-Nan Gong, Erinna F Lee, et al.The Biochemical Journal|November 14, 2013
Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKLJames M Murphy, Isabelle S Lucet, Joanne M Hildebrand, et al.Analytical Biochemistry|May 26, 2005
Fluorescence and analytical ultracentrifugation analyses of the interaction of the tyrosine kinase inhibitor, tyrphostin AG 1478-mesylate, with albuminAndrew H A Clayton, Matthew A Perugini, Janet Weinstock, et al.Blood|July 29, 2016
Hierarchy for targeting prosurvival BCL2 family proteins in multiple myeloma: pivotal role of MCL1Jia-Nan Gong, Tiffany Khong, David Segal, et al.ACS Medicinal Chemistry Letters|June 20, 2014
Structure-Guided Rescaffolding of Selective Antagonists of BCL-XLMichael F T Koehler, Philippe Bergeron, Edna F Choo, et al.Blood Advances|October 5, 2020
BCL-XL inhibition by BH3-mimetic drugs induces apoptosis in models of Epstein-Barr virus-associated T/NK-cell lymphomaNenad Sejic, Lindsay C George, Rosemary J Tierney, et al.Bioorganic & Medicinal Chemistry Letters|December 30, 2006
Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screeningGeorgina A Holloway, Jonathan B Baell, Alan H Fairlamb, et al.Cell|December 20, 2014
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN productionMichael J White, Kate McArthur, Donald Metcalf, et al.Pageof 12