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Current Pharmaceutical Design|May 25, 2013
Cancer therapy: Targeting mitochondria and other sub-cellular organellesObinna C Ubah, Heather M Wallace
Journal of Immunology Research|February 25, 2020
In Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA: An Encouraging Milestone to Further Clinical Drug DevelopmentObinna C Ubah, Andrew J Porter, Caroline J Barelle
Frontiers in Immunology|April 11, 2019
An Anti-hTNF-α Variable New Antigen Receptor Format Demonstrates Superior in vivo Preclinical Efficacy to Humira® in a Transgenic Mouse Autoimmune Polyarthritis Disease ModelObinna C Ubah, John Steven, Andrew J Porter, et al.
Methods in Molecular Biology (Clifton, N.J.)|February 14, 2022
Overview, Generation, and Significance of Variable New Antigen Receptors (VNARs) as a Platform for Drug and Diagnostic DevelopmentSamata S Pandey, Marina Kovaleva, Caroline J Barelle, et al.
Current Pharmaceutical Design|September 9, 2016
Phage Display Derived IgNAR V Region Binding Domains for Therapeutic DevelopmentObinna C Ubah, Caroline J Barelle, Magdalena J Buschhaus, et al.
Methods in Molecular Biology (Clifton, N.J.)|October 19, 2019
In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical PropertiesJohn Steven, Obinna C Ubah, Magdalena Buschhaus, et al.
Biochemical Society Transactions|November 2, 2018
Next-generation flexible formats of VNAR domains expand the drug platform's utility and developabilityObinna C Ubah, Magdalena J Buschhaus, Laura Ferguson, et al.
Frontiers in Immunology|January 10, 2018
Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic DevelopmentObinna C Ubah, John Steven, Marina Kovaleva, et al.
Translational Vision Science & Technology|October 8, 2019
Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory LigandKathryn L Pepple, Leslie Wilson, Russell N Van Gelder, et al.
Frontiers in Immunology|November 8, 2017
In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical DevelopmentJohn Steven, Mischa R Müller, Miguel F Carvalho, et al.
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