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Bioorganic & Medicinal Chemistry Letters
|
December 3, 2014
Discovery of potent iminoheterocycle BACE1 inhibitors
John P Caldwell, Robert D Mazzola, James Durkin, et al.
Chembiochem : a European Journal of Chemical Biology
|
February 1, 2020
Cyp1 Inhibition Prevents Doxorubicin-Induced Cardiomyopathy in a Zebrafish Heart-Failure Model
Pui-Ying Lam, Peter Kutchukian, Rajan Anand, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 21, 2010
Iminoheterocycles as gamma-secretase modulators
John P Caldwell, Chad E Bennett, Troy M McCracken, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 3, 2009
The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety
Ginny D Ho, John Anthes, Ana Bercovici, et al.
Journal of Medicinal Chemistry
|
November 3, 2018
Overcoming Time-Dependent Inhibition (TDI) of Cytochrome P450 3A4 (CYP3A4) Resulting from Bioactivation of a Fluoropyrimidine Moiety
Mihirbaran Mandal, Kaushik Mitra, Diane Grotz, et al.
Journal of Medicinal Chemistry
|
September 20, 2012
Design and validation of bicyclic iminopyrimidinones as beta amyloid cleaving enzyme-1 (BACE1) inhibitors: conformational constraint to favor a bioactive conformation
Mihirbaran Mandal, Zhaoning Zhu, Jared N Cumming, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 3, 2015
Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors
Brian A McKittrick, John P Caldwell, Thomas Bara, et al.
Journal of Medicinal Chemistry
|
March 4, 2016
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates
Mihirbaran Mandal, Yusheng Wu, Jeffrey Misiaszek, et al.
ACS Medicinal Chemistry Letters
|
April 15, 2026
DNA-Encoded Library (DEL) Selection Identifies a Distinct DDB1 Ligand Binding Site
Shiva Krishna Reddy Guduru, John P Caldwell, Katherine M Digianantonio, et al.
Journal of Medicinal Chemistry
|
March 22, 2017
Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO Inhibitor
Mihirbaran Mandal, Zheng Tan, Christina Madsen-Duggan, et al.
Page
of 14
Search research articles
Search
Showing results (121-130 of 132) with videos related to
Sort By:
Page
of 14
Bioorganic & Medicinal Chemistry Letters
|
December 3, 2014
Discovery of potent iminoheterocycle BACE1 inhibitors
John P Caldwell, Robert D Mazzola, James Durkin, et al.
Chembiochem : a European Journal of Chemical Biology
|
February 1, 2020
Cyp1 Inhibition Prevents Doxorubicin-Induced Cardiomyopathy in a Zebrafish Heart-Failure Model
Pui-Ying Lam, Peter Kutchukian, Rajan Anand, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 21, 2010
Iminoheterocycles as gamma-secretase modulators
John P Caldwell, Chad E Bennett, Troy M McCracken, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 3, 2009
The discovery of tropane derivatives as nociceptin receptor ligands for the management of cough and anxiety
Ginny D Ho, John Anthes, Ana Bercovici, et al.
Journal of Medicinal Chemistry
|
November 3, 2018
Overcoming Time-Dependent Inhibition (TDI) of Cytochrome P450 3A4 (CYP3A4) Resulting from Bioactivation of a Fluoropyrimidine Moiety
Mihirbaran Mandal, Kaushik Mitra, Diane Grotz, et al.
Journal of Medicinal Chemistry
|
September 20, 2012
Design and validation of bicyclic iminopyrimidinones as beta amyloid cleaving enzyme-1 (BACE1) inhibitors: conformational constraint to favor a bioactive conformation
Mihirbaran Mandal, Zhaoning Zhu, Jared N Cumming, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 3, 2015
Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors
Brian A McKittrick, John P Caldwell, Thomas Bara, et al.
Journal of Medicinal Chemistry
|
March 4, 2016
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates
Mihirbaran Mandal, Yusheng Wu, Jeffrey Misiaszek, et al.
ACS Medicinal Chemistry Letters
|
April 15, 2026
DNA-Encoded Library (DEL) Selection Identifies a Distinct DDB1 Ligand Binding Site
Shiva Krishna Reddy Guduru, John P Caldwell, Katherine M Digianantonio, et al.
Journal of Medicinal Chemistry
|
March 22, 2017
Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO Inhibitor
Mihirbaran Mandal, Zheng Tan, Christina Madsen-Duggan, et al.
Page
of 14