Showing results (741-750 of 1,123) with videos related to
Sort By:
Pageof 113
Bioorganic & Medicinal Chemistry Letters|December 25, 2010
Discovery of molecular switches within the ADX-47273 mGlu5 PAM scaffold that modulate modes of pharmacology to afford potent mGlu5 NAMs, PAMs and partial antagonistsJeffrey P Lamb, Darren W Engers, Colleen M Niswender, et al.Bioorganic & Medicinal Chemistry Letters|February 17, 2010
Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: development of a potent and highly selective M1 PAMThomas M Bridges, J Phillip Kennedy, Meredith J Noetzel, et al.The Journal of Pharmacology and Experimental Therapeutics|March 11, 2018
Total RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M4 Muscarinic Receptor as a Novel Therapeutic TargetRocco G Gogliotti, Nicole M Fisher, Branden J Stansley, et al.The Journal of Pharmacology and Experimental Therapeutics|April 10, 2007
A novel family of potent negative allosteric modulators of group II metabotropic glutamate receptorsKamondanai Hemstapat, Herve Da Costa, Yi Nong, et al.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference|November 17, 2018
Prediction of One-Year Transplant-Free Survival after Norwood Procedure Based on the Pre-Operative DataM Luis Ahumadal, Jacquelin Peck, Jorge Guerra, et al.Bioorganic & Medicinal Chemistry Letters|February 27, 2017
Continued optimization of the M5 NAM ML375: Discovery of VU6008667, an M5 NAM with high CNS penetration and a desired short half-life in rat for addiction studiesKevin M McGowan, Kellie D Nance, Hykeyung P Cho, et al.ACS Chemical Neuroscience|October 29, 2010
Discovery of a Novel Chemical Class of mGlu(5) Allosteric Ligands with Distinct Modes of PharmacologyAlexis S Hammond, Alice L Rodriguez, Steven D Townsend, et al.Journal of Clinical Gastroenterology|September 1, 2017
Rate of Nonsurveillance and Advanced Hepatocellular Carcinoma at Diagnosis in Chronic Liver DiseaseYi Huang, Michael C Wallace, Leon A Adams, et al.Chemical Reviews|February 17, 2016
Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate ReceptorsCraig W Lindsley, Kyle A Emmitte, Corey R Hopkins, et al.The Journal of Pharmacology and Experimental Therapeutics|April 13, 2006
Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in miceRuggero Galici, Carrie K Jones, Kamondanai Hemstapat, et al.Pageof 113