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Journal of Medicinal Chemistry|September 1, 2000
Crystal structures of human factor Xa complexed with potent inhibitorsS Maignan, J P Guilloteau, S Pouzieux, et al.Journal of Cardiovascular Pharmacology|December 22, 1999
Pharmacodynamic activity and antithrombotic efficacy of RPR120844, a novel inhibitor of coagulation factor XaR J Leadley, S R Morgan, R Bentley, et al.Bioorganic & Medicinal Chemistry Letters|June 1, 2002
Optimization of the beta-aminoester class of factor Xa inhibitors. Part 1: P(4) and side-chain modifications for improved in vitro potencyMark Czekaj, Scott I Klein, Kevin R Guertin, et al.Drug and Chemical Toxicology|September 11, 2024
Exploring the toxicity profile of coriander (<i>C. sativum</i> L.) essential oil: implications for translational toxicological researchDavid H X Barbosa, Danielle da N Alves, Patrícia N Andrade, et al.Hepatology (Baltimore, Md.)|August 1, 2018
Emricasan (IDN-6556) Lowers Portal Pressure in Patients With Compensated Cirrhosis and Severe Portal HypertensionGuadalupe Garcia-Tsao, Michael Fuchs, Mitchell Shiffman, et al.Journal of Medicinal Chemistry|March 4, 1998
Identification and initial structure-activity relationships of a novel class of nonpeptide inhibitors of blood coagulation factor XaS I Klein, M Czekaj, C J Gardner, et al.Bioorganic & Medicinal Chemistry Letters|October 6, 1999
Synthesis, SAR and in vivo activity of novel thienopyridine sulfonamide pyrrolidinones as factor Xa inhibitorsM R Becker, W R Ewing, R S Davis, et al.Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association|June 19, 2018
Emricasan Improves Liver Function in Patients With Cirrhosis and High Model for End-Stage Liver Disease Scores Compared With PlaceboCatherine T Frenette, Giuseppe Morelli, Mitchell L Shiffman, et al.Bioorganic & Medicinal Chemistry Letters|June 1, 2002
Optimization of the beta-aminoester class of factor Xa inhibitors. Part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activityKevin R Guertin, Charles J Gardner, Scott I Klein, et al.Journal of Medicinal Chemistry|September 10, 1999
Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor XaW R Ewing, M R Becker, V E Manetta, et al.Pageof 5