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Expert Opinion on Therapeutic Patents
|
December 2, 2014
Sirtuin modulators: an updated patent review (2012 - 2014)
Paolo Mellini, Sergio Valente, Antonello Mai
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
July 9, 2014
Studying SIRT6 regulation using H3K56 based substrate and small molecules
Piia Kokkonen, Minna Rahnasto-Rilla, Paolo Mellini, et al.
BMC Cancer
|
August 8, 2018
Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines
Tomohiro Kozako, Paolo Mellini, Takeo Ohsugi, et al.
Neuropharmacology
|
February 11, 2017
SIRT2 inhibition modulate glutamate and serotonin systems in the prefrontal cortex and induces antidepressant-like action
Mercedes Erburu, Irene Muñoz-Cobo, Teresa Diaz-Perdigon, et al.
Journal of Medicinal Chemistry
|
August 10, 2013
Screen of pseudopeptidic inhibitors of human sirtuins 1-3: two lead compounds with antiproliferative effects in cancer cells
Paolo Mellini, Tarja Kokkola, Tiina Suuronen, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
April 22, 2014
Quantitative insights for the design of substrate-based SIRT1 inhibitors
Piia Kokkonen, Paolo Mellini, Olli Nyrhilä, et al.
Chemical Science
|
October 10, 2017
Potent mechanism-based sirtuin-2-selective inhibition by an <i>in situ</i>-generated occupant of the substrate-binding site, "selectivity pocket" and NAD<sup>+</sup>-binding site
Paolo Mellini, Yukihiro Itoh, Hiroki Tsumoto, et al.
Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|
April 25, 2018
Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells
Paolo Mellini, Biagina Marrocco, Diana Borovika, et al.
European Journal of Medicinal Chemistry
|
February 11, 2012
Synthesis and antifungal activity of a new series of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives
Daniela De Vita, Luigi Scipione, Silvano Tortorella, et al.
Chemmedchem
|
October 25, 2013
Carprofen analogues as sirtuin inhibitors: enzyme and cellular studies
Paolo Mellini, Vincenzo Carafa, Barbara Di Rienzo, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 16) with videos related to
Sort By:
Page
of 2
Expert Opinion on Therapeutic Patents
|
December 2, 2014
Sirtuin modulators: an updated patent review (2012 - 2014)
Paolo Mellini, Sergio Valente, Antonello Mai
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
July 9, 2014
Studying SIRT6 regulation using H3K56 based substrate and small molecules
Piia Kokkonen, Minna Rahnasto-Rilla, Paolo Mellini, et al.
BMC Cancer
|
August 8, 2018
Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines
Tomohiro Kozako, Paolo Mellini, Takeo Ohsugi, et al.
Neuropharmacology
|
February 11, 2017
SIRT2 inhibition modulate glutamate and serotonin systems in the prefrontal cortex and induces antidepressant-like action
Mercedes Erburu, Irene Muñoz-Cobo, Teresa Diaz-Perdigon, et al.
Journal of Medicinal Chemistry
|
August 10, 2013
Screen of pseudopeptidic inhibitors of human sirtuins 1-3: two lead compounds with antiproliferative effects in cancer cells
Paolo Mellini, Tarja Kokkola, Tiina Suuronen, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|
April 22, 2014
Quantitative insights for the design of substrate-based SIRT1 inhibitors
Piia Kokkonen, Paolo Mellini, Olli Nyrhilä, et al.
Chemical Science
|
October 10, 2017
Potent mechanism-based sirtuin-2-selective inhibition by an <i>in situ</i>-generated occupant of the substrate-binding site, "selectivity pocket" and NAD<sup>+</sup>-binding site
Paolo Mellini, Yukihiro Itoh, Hiroki Tsumoto, et al.
Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|
April 25, 2018
Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells
Paolo Mellini, Biagina Marrocco, Diana Borovika, et al.
European Journal of Medicinal Chemistry
|
February 11, 2012
Synthesis and antifungal activity of a new series of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives
Daniela De Vita, Luigi Scipione, Silvano Tortorella, et al.
Chemmedchem
|
October 25, 2013
Carprofen analogues as sirtuin inhibitors: enzyme and cellular studies
Paolo Mellini, Vincenzo Carafa, Barbara Di Rienzo, et al.
Page
of 2