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Expert Opinion on Drug Discovery
|
September 21, 2019
Estimating human ADME properties, pharmacokinetic parameters and likely clinical dose in drug discovery
Adam J Lucas, Joanne L Sproston, Patrick Barton, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
May 17, 2012
The development, characterization, and application of an OATP1B1 inhibition assay in drug discovery
Matthew G Soars, Patrick Barton, Manfred Ismair, et al.
Journal of Medicinal Chemistry
|
August 5, 2005
A rapid computational filter for cytochrome P450 1A2 inhibition potential of compound libraries
Kamaldeep K Chohan, Stuart W Paine, Jaina Mistry, et al.
Drug Discovery Today
|
April 16, 2022
Multimodal molecular imaging in drug discovery and development
Isabeau Vermeulen, Emre M Isin, Patrick Barton, et al.
Angewandte Chemie (International Ed. in English)
|
October 19, 2002
Transmembrane signalling
Patrick Barton, Christopher A Hunter, Timothy J Potter, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
November 16, 2002
The influence of nonspecific microsomal binding on apparent intrinsic clearance, and its prediction from physicochemical properties
Rupert P Austin, Patrick Barton, Scott L Cockroft, et al.
Journal of Medicinal Chemistry
|
March 21, 2003
A comparison of physiochemical property profiles of development and marketed oral drugs
Mark C Wenlock, Rupert P Austin, Patrick Barton, et al.
Pharmaceutical Research
|
September 24, 2005
The thermodynamics of the partitioning of ionizing molecules between aqueous buffers and phospholipid membranes
Rupert P Austin, Patrick Barton, Andrew M Davis, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
January 15, 2014
Application of an in vitro OAT assay in drug design and optimization of renal clearance
Matthew G Soars, Patrick Barton, Lisa L Elkin, et al.
Journal of Pharmaceutical and Biomedical Analysis
|
March 9, 2017
Bioanalysis of Pseudomonas aeruginosa alkyl quinolone signalling molecules in infected mouse tissue using LC-MS/MS; and its application to a pharmacodynamic evaluation of MvfR inhibition
Paul Turnpenny, Anthony Padfield, Patrick Barton, et al.
Page
of 3
Search research articles
Search
Showing results (11-20 of 28) with videos related to
Sort By:
Page
of 3
Expert Opinion on Drug Discovery
|
September 21, 2019
Estimating human ADME properties, pharmacokinetic parameters and likely clinical dose in drug discovery
Adam J Lucas, Joanne L Sproston, Patrick Barton, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
May 17, 2012
The development, characterization, and application of an OATP1B1 inhibition assay in drug discovery
Matthew G Soars, Patrick Barton, Manfred Ismair, et al.
Journal of Medicinal Chemistry
|
August 5, 2005
A rapid computational filter for cytochrome P450 1A2 inhibition potential of compound libraries
Kamaldeep K Chohan, Stuart W Paine, Jaina Mistry, et al.
Drug Discovery Today
|
April 16, 2022
Multimodal molecular imaging in drug discovery and development
Isabeau Vermeulen, Emre M Isin, Patrick Barton, et al.
Angewandte Chemie (International Ed. in English)
|
October 19, 2002
Transmembrane signalling
Patrick Barton, Christopher A Hunter, Timothy J Potter, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
November 16, 2002
The influence of nonspecific microsomal binding on apparent intrinsic clearance, and its prediction from physicochemical properties
Rupert P Austin, Patrick Barton, Scott L Cockroft, et al.
Journal of Medicinal Chemistry
|
March 21, 2003
A comparison of physiochemical property profiles of development and marketed oral drugs
Mark C Wenlock, Rupert P Austin, Patrick Barton, et al.
Pharmaceutical Research
|
September 24, 2005
The thermodynamics of the partitioning of ionizing molecules between aqueous buffers and phospholipid membranes
Rupert P Austin, Patrick Barton, Andrew M Davis, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
January 15, 2014
Application of an in vitro OAT assay in drug design and optimization of renal clearance
Matthew G Soars, Patrick Barton, Lisa L Elkin, et al.
Journal of Pharmaceutical and Biomedical Analysis
|
March 9, 2017
Bioanalysis of Pseudomonas aeruginosa alkyl quinolone signalling molecules in infected mouse tissue using LC-MS/MS; and its application to a pharmacodynamic evaluation of MvfR inhibition
Paul Turnpenny, Anthony Padfield, Patrick Barton, et al.
Page
of 3