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Bioorganic & Medicinal Chemistry Letters|November 28, 2016
The use of molecular dynamics simulations to evaluate the DNA sequence-selectivity of G-A cross-linking PBD-duocarmycin dimersPaul J M Jackson, Khondaker M Rahman, David E ThurstonDrug Discovery Today. Technologies|December 17, 2018
Use of pyrrolobenzodiazepines and related covalent-binding DNA-interactive molecules as ADC payloads: Is mechanism related to systemic toxicity?Paul J M Jackson, Syafiq Kay, Ilona Pysz, et al.Angewandte Chemie (International Ed. in English)|November 19, 2016
From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody-Drug Conjugates (ADCs)Julia Mantaj, Paul J M Jackson, Khondaker M Rahman, et al.Plos One|April 8, 2016
Covalent Bonding of Pyrrolobenzodiazepines (PBDs) to Terminal Guanine Residues within Duplex and Hairpin DNA FragmentsJulia Mantaj, Paul J M Jackson, Kersti Karu, et al.Organic & Biomolecular Chemistry|March 4, 2015
Effect of hairpin loop structure on reactivity, sequence preference and adduct orientation of a DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumour agentDavid E Thurston, Higia Vassoler, Paul J M Jackson, et al.Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|May 4, 2020
UPLC-based assay to assess the hydrophobicity of Antibody-Drug Conjugate (ADC) payloadsIlona Pysz, Paul J M Jackson, David J Barlow, et al.ACS Chemical Biology|August 12, 2014
Computational studies support the role of the C7-sibirosamine sugar of the pyrrolobenzodiazepine (PBD) sibiromycin in transcription factor inhibitionPaul J M Jackson, Colin H James, Terence C Jenkins, et al.Biophysical Chemistry|September 25, 2017
Sequence-selective binding of C8-conjugated pyrrolobenzodiazepines (PBDs) to DNAMohammad A Basher, Khondaker Miraz Rahman, Paul J M Jackson, et al.Plos One|August 19, 2014
Pyrrolobenzodiazepines (PBDs) do not bind to DNA G-quadruplexesKhondaker M Rahman, David B Corcoran, Tam T T Bui, et al.Bioorganic & Medicinal Chemistry Letters|January 8, 2025
Synthesis of novel pyrrolobenzodiazepine (PBD) C1-substituted monomers and dimers with DNA-binding activity and cytotoxicityGeorge Procopiou, Paul J M Jackson, Paolo Andriollo, et al.Pageof 2