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Communications Biology|August 5, 2022
Structure of human spermine oxidase in complex with a highly selective allosteric inhibitorElsie Diaz, Suraj Adhikary, Armand W J W Tepper, et al.Journal of Medicinal Chemistry|December 22, 2016
The Discovery and Hit-to-Lead Optimization of Tricyclic Sulfonamides as Potent and Efficacious Potentiators of Glycine ReceptorsHoward Bregman, Jeffrey R Simard, Kristin L Andrews, et al.Molecular Cancer Therapeutics|March 3, 2026
JNJ-79032421, a Novel Membrane-restricted Mesothelin-targeting T-cell-engaging Bispecific Antibody for the Treatment of Mesothelin-positive CancersKarine Smans, Thomas Nesspor, Sabine De Breucker, et al.Journal of Medicinal Chemistry|January 15, 2015
Discovery of 1H-pyrazol-3(2H)-ones as potent and selective inhibitors of protein kinase R-like endoplasmic reticulum kinase (PERK)Adrian L Smith, Kristin L Andrews, Holger Beckmann, et al.Bioorganic & Medicinal Chemistry Letters|July 7, 2012
Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitorsEmily A Peterson, Alessandro A Boezio, Paul S Andrews, et al.Blood|June 21, 2024
Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemiasMin Chul Kwon, Jan Willem Thuring, Olivier Querolle, et al.Proceedings of the National Academy of Sciences of the United States of America|December 26, 2023
Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammationHolger Babbe, Thomas B Sundberg, Mark Tichenor, et al.Pageof 5