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Paul Rowland

Showing results (21-30 of 41) with videos related to

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Journal of Medicinal Chemistry|April 12, 2017
Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute PancreatitisAnn L Walker, Nicolas Ancellin, Benjamin Beaufils, et al.
Bioorganic & Medicinal Chemistry Letters|May 2, 2009
Second generation of BACE-1 inhibitors part 3: Towards non hydroxyethylamine transition state mimeticsNicolas Charrier, Brian Clarke, Leanne Cutler, et al.
Bioorganic & Medicinal Chemistry Letters|May 12, 2009
Second generation of BACE-1 inhibitors. Part 1: The need for improved pharmacokineticsNicolas Charrier, Brian Clarke, Leanne Cutler, et al.
Bioorganic & Medicinal Chemistry Letters|March 25, 2017
The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitisJohn Liddle, Benjamin Beaufils, Margaret Binnie, et al.
Journal of Medicinal Chemistry|May 7, 2008
Second generation of hydroxyethylamine BACE-1 inhibitors: optimizing potency and oral bioavailabilityNicolas Charrier, Brian Clarke, Leanne Cutler, et al.
Bioorganic & Medicinal Chemistry Letters|January 4, 2008
BACE-1 inhibitors part 1: identification of novel hydroxy ethylamines (HEAs)Brian Clarke, Emmanuel Demont, Colin Dingwall, et al.
Bioorganic & Medicinal Chemistry Letters|January 2, 2008
BACE-1 inhibitors part 2: identification of hydroxy ethylamines (HEAs) with reduced peptidic characterBrian Clarke, Emmanuel Demont, Colin Dingwall, et al.
Journal of Medicinal Chemistry|August 25, 2015
Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory DiseaseKenneth Down, Augustin Amour, Ian R Baldwin, et al.
Journal of Medicinal Chemistry|December 20, 2019
Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity TargetZoë A Henley, Augustin Amour, Nick Barton, et al.
Journal of Medicinal Chemistry|September 13, 2021
Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding ModeKenneth Down, Augustin Amour, Niall A Anderson, et al.
Pageof 5

Showing results (21-30 of 41) with videos related to

Sort By:
Pageof 5
Journal of Medicinal Chemistry|April 12, 2017
Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute PancreatitisAnn L Walker, Nicolas Ancellin, Benjamin Beaufils, et al.
Bioorganic & Medicinal Chemistry Letters|May 2, 2009
Second generation of BACE-1 inhibitors part 3: Towards non hydroxyethylamine transition state mimeticsNicolas Charrier, Brian Clarke, Leanne Cutler, et al.
Bioorganic & Medicinal Chemistry Letters|May 12, 2009
Second generation of BACE-1 inhibitors. Part 1: The need for improved pharmacokineticsNicolas Charrier, Brian Clarke, Leanne Cutler, et al.
Bioorganic & Medicinal Chemistry Letters|March 25, 2017
The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitisJohn Liddle, Benjamin Beaufils, Margaret Binnie, et al.
Journal of Medicinal Chemistry|May 7, 2008
Second generation of hydroxyethylamine BACE-1 inhibitors: optimizing potency and oral bioavailabilityNicolas Charrier, Brian Clarke, Leanne Cutler, et al.
Bioorganic & Medicinal Chemistry Letters|January 4, 2008
BACE-1 inhibitors part 1: identification of novel hydroxy ethylamines (HEAs)Brian Clarke, Emmanuel Demont, Colin Dingwall, et al.
Bioorganic & Medicinal Chemistry Letters|January 2, 2008
BACE-1 inhibitors part 2: identification of hydroxy ethylamines (HEAs) with reduced peptidic characterBrian Clarke, Emmanuel Demont, Colin Dingwall, et al.
Journal of Medicinal Chemistry|August 25, 2015
Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory DiseaseKenneth Down, Augustin Amour, Ian R Baldwin, et al.
Journal of Medicinal Chemistry|December 20, 2019
Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity TargetZoë A Henley, Augustin Amour, Nick Barton, et al.
Journal of Medicinal Chemistry|September 13, 2021
Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding ModeKenneth Down, Augustin Amour, Niall A Anderson, et al.
Pageof 5