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Journal of Biomolecular Screening|February 12, 2010
Detection of the ATPase activity of the molecular chaperones Hsp90 and Hsp72 using the TranscreenerTM ADP assay kitMartin Rowlands, Craig McAndrew, Chris Prodromou, et al.Cell Cycle (Georgetown, Tex.)|April 8, 2010
Targeting HSP70: the second potentially druggable heat shock protein and molecular chaperone?Marissa V Powers, Keith Jones, Caterina Barillari, et al.Nature Reviews. Drug Discovery|July 23, 2016
Drug discovery in advanced prostate cancer: translating biology into therapyTimothy A Yap, Alan D Smith, Roberta Ferraldeschi, et al.Molecular Cancer Therapeutics|March 18, 2004
Cassette dosing pharmacokinetics of a library of 2,6,9-trisubstituted purine cyclin-dependent kinase 2 inhibitors prepared by parallel synthesisFlorence I Raynaud, Peter M Fischer, Bernard P Nutley, et al.Cancer Research|June 3, 2005
Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factorsNoan-Minh Chau, Paul Rogers, Wynne Aherne, et al.Chemistry (Weinheim an Der Bergstrasse, Germany)|January 21, 2010
Targeting the Hsp90 chaperone: synthesis of novel resorcylic acid macrolactone inhibitors of Hsp90James E H Day, Swee Y Sharp, Martin G Rowlands, et al.Current Opinion in Pharmacology|August 30, 2008
Targeting the PI3K-AKT-mTOR pathway: progress, pitfalls, and promisesTimothy A Yap, Michelle D Garrett, Mike I Walton, et al.Journal of Medicinal Chemistry|December 23, 2016
Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic ScreenMatthew D Cheeseman, Nicola E A Chessum, Carl S Rye, et al.Oncotarget|July 16, 2013
Combining trail with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signalingGrazia Saturno, Melanie Valenti, Alexis De Haven Brandon, et al.Organic & Biomolecular Chemistry|April 2, 2016
Fused imidazoles as potential chemical scaffolds for inhibition of heat shock protein 70 and induction of apoptosis. Synthesis and biological evaluation of phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthrolinesAlpa Patel, Swee Y Sharp, Katelan Hall, et al.Pageof 30